バックグラウンド: | HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare, ' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]). |
UniProt Protein Function: | Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. |
NCBI Summary: | HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010] |
UniProt Code: | Q96CS2 |
NCBI GenInfo Identifier: | 19923971 |
NCBI Gene ID: | 115106 |
NCBI Accession: | NP_612452.1 |
UniProt Secondary Accession: | Q96CS2,Q8N837, B2RDM7, |
UniProt Related Accession: | Q96CS2 |
Molecular Weight: | 22,744 Da |
NCBI Full Name: | HAUS augmin-like complex subunit 1 |
NCBI Synonym Full Names: | HAUS augmin like complex subunit 1 |
NCBI Official Symbol: | HAUS1 |
NCBI Official Synonym Symbols: | HEIC; CCDC5; HEI-C; HsT1461 |
NCBI Protein Information: | HAUS augmin-like complex subunit 1 |
UniProt Protein Name: | HAUS augmin-like complex subunit 1 |
UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 5; Enhancer of invasion-cluster; HEI-C |
Protein Family: | HAUS augmin-like complex |
UniProt Gene Name: | HAUS1 |