| バックグラウンド: | The protein encoded by this gene, glutathione S-transferase (GST) theta 2B (GSTT2B), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2B gene is a pseudogene in some populations. |
| UniProt Protein Function: | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. |
| NCBI Summary: | The protein encoded by this gene, glutathione S-transferase (GST) theta 2 (GSTT2), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations. [provided by RefSeq, Sep 2015] |
| UniProt Code: | P0CG30 |
| NCBI GenInfo Identifier: | 702760663 |
| NCBI Gene ID: | 2953 |
| NCBI Accession: | NP_000845.2 |
| UniProt Secondary Accession: | P0CG30,O60665, P30712, Q6IPV7, Q9HD76, |
| UniProt Related Accession: | P0CG29 |
| Molecular Weight: | 27,507 Da |
| NCBI Full Name: | glutathione S-transferase theta-2 isoform a |
| NCBI Synonym Full Names: | glutathione S-transferase theta 2 (gene/pseudogene) |
| NCBI Official Symbol: | GSTT2 |
| NCBI Protein Information: | glutathione S-transferase theta-2 |
| UniProt Protein Name: | Glutathione S-transferase theta-2B |
| UniProt Synonym Protein Names: | GST class-theta-2; Glutathione S-transferase theta-2 |
| Protein Family: | Glutathione S-transferase |
| UniProt Gene Name: | GSTT2B |
