Anti-GSTT1 Antibody (CAB13996)
- SKU:
- CAB13996
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GSTT1 Antibody |
| 抗体コード: | CAB13996 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human GSTT1 (NP_000844.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | MCF7, HepG2, U-87MG, Mouse liver, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human GSTT1 (NP_000844.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MGLE LYLD LLSQ PCRA VYIF AKKN DIPF ELRI VDLI KGQH LSDA FAQV NPLK KVPA LKDG DFTL TESV AILL YLTR KYKV PDYW YPQD LQAR ARVD EYLA WQHT TLRR SCLR ALWH KVMF PVFL GEPV SPQT LAAT LAEL DVTL QLLE DKFL QNKA FLTG PHIS LADL VAIT ELMH PVGA GCQV FEGR PKLA TWRQ RVEA AVGE DLFQ EAHE VILK AKDF PPAD PTIK QKLM PWVL AMIR |
| 遺伝子ID: | 2952 |
| Uniprot: | P30711 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 13kDa/27kDa |
| 観察された分子量: | 27kDa |
| 同義語: | GSTT1 |
| バックグラウンド: | The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. |
| UniProt Protein Function: | GSTT1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2- epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4- nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide. Belongs to the GST superfamily. Theta family. |
| UniProt Protein Details: | Protein type:Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450; Other Amino Acids Metabolism - glutathione; Transferase; EC 2.5.1.18 Chromosomal Location of Human Ortholog: 22q11.23 Cellular Component: cytosol Molecular Function:glutathione peroxidase activity; glutathione transferase activity Biological Process: glutathione metabolic process |
| NCBI Summary: | The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| UniProt Code: | P30711 |
| NCBI GenInfo Identifier: | 21264427 |
| NCBI Gene ID: | 2952 |
| NCBI Accession: | P30711.4 |
| UniProt Secondary Accession: | P30711,O00226, Q5TZY2, Q6IC69, Q969K8, Q96IY3, |
| UniProt Related Accession: | P30711 |
| Molecular Weight: | 13,517 Da |
| NCBI Full Name: | Glutathione S-transferase theta-1 |
| NCBI Synonym Full Names: | glutathione S-transferase theta 1 |
| NCBI Official Symbol: | GSTT1 |
| NCBI Protein Information: | glutathione S-transferase theta-1 |
| UniProt Protein Name: | Glutathione S-transferase theta-1 |
| UniProt Synonym Protein Names: | GST class-theta-1; Glutathione transferase T1-1 |
| Protein Family: | Glutathione S-transferase |
| UniProt Gene Name: | GSTT1 |
| UniProt Entry Name: | GSTT1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GSTT1 antibody (CAB13996) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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