Anti-GSTO1 Antibody (CAB15354)
- SKU:
- CAB15354
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GSTO1 Antibody |
| 抗体コード: | CAB15354 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-241 of human GSTO1 (NP_004823.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | LO2, BxPC-3, HT-29, HeLa, Mouse heart, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-241 of human GSTO1 (NP_004823.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSGE SARS LGKG SAPP GPVP EGSI RIYS MRFC PFAE RTRL VLKA KGIR HEVI NINL KNKP EWFF KKNP FGLV PVLE NSQG QLIY ESAI TCEY LDEA YPGK KLLP DDPY EKAC QKMI LELF SKVP SLVG SFIR SQNK EDYA GLKE EFRK EFTK LEEV LTNK KTTF FGGN SISM IDYL IWPW FERL EAMK LNEC VDHT PKLK LWMA AMKE DPTV SALL TSEK DWQG FLEL YLQN SPEA CDYG L |
| 遺伝子ID: | 9446 |
| Uniprot: | P78417 |
| セルラーロケーション: | Cytoplasm, cytosol |
| 計算された分子量: | 23kDa/24kDa/27kDa |
| 観察された分子量: | 27kDa |
| 同義語: | GSTO1, GSTO 1-1, GSTTLp28, HEL-S-21, P28, SPG-R, GSTO1-1 |
| バックグラウンド: | The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | GSTO1: Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. |
| UniProt Protein Details: | Protein type:EC 1.8.5.1; Transferase; EC 1.20.4.2; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.5.1.18; Other Amino Acids Metabolism - glutathione; Xenobiotic Metabolism - drug metabolism - cytochrome P450 Chromosomal Location of Human Ortholog: 10q25.1 Cellular Component: cytoplasm; cytosol Molecular Function:glutathione dehydrogenase (ascorbate) activity; glutathione transferase activity; methylarsonate reductase activity; oxidoreductase activity; protein binding Biological Process: glutathione metabolic process; L-ascorbic acid metabolic process; methylation; positive regulation of skeletal muscle contraction via regulation of the release of sequestered calcium ion; xenobiotic catabolic process |
| NCBI Summary: | The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| UniProt Code: | P78417 |
| NCBI GenInfo Identifier: | 6016173 |
| NCBI Gene ID: | 9446 |
| NCBI Accession: | P78417.2 |
| UniProt Secondary Accession: | P78417,Q5TA03, Q7Z3T2, D3DRA3, F5H7H0, |
| UniProt Related Accession: | P78417 |
| Molecular Weight: | 24,796 Da |
| NCBI Full Name: | Glutathione S-transferase omega-1 |
| NCBI Synonym Full Names: | glutathione S-transferase omega 1 |
| NCBI Official Symbol: | GSTO1 |
| NCBI Official Synonym Symbols: | P28; SPG-R; GSTO 1-1; GSTTLp28; HEL-S-21 |
| NCBI Protein Information: | glutathione S-transferase omega-1 |
| UniProt Protein Name: | Glutathione S-transferase omega-1 |
| UniProt Synonym Protein Names: | Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase (EC:1.8.5.1 |
| Protein Family: | Glutathione S-transferase |
| UniProt Gene Name: | GSTO1 |
| UniProt Entry Name: | GSTO1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GSTO1 antibody (CAB15354) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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