Anti-GSTK1 Antibody (CAB19963)[KO Validated]

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SKU:
CAB19963
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

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抗体名:Anti-GSTK1 Antibody [KO Validated]
抗体コード:CAB19963
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IHC IF
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant protein of human GSTK1.
申し込み:WB IHC IF
推奨希釈:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
反応性:Human, Mouse, Rat
ポジティブサンプル:293T
免疫原:Recombinant protein of human GSTK1.
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:373156
Uniprot:Q9Y2Q3
セルラーロケーション:Peroxisome
計算された分子量:20kDa/24kDa/25kDa/31kDa
観察された分子量:23KDa
Anti-GSTK1 Antibody [KO Validated] (CAB19963)Western blot analysis of extracts from normal (control) and GSTK1 knockout (KO) 293T cells, using GSTK1 antibody (CAB19963) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
同義語:GSTK1, GST, GST 13-13, GST13, GST13-13, GSTK1-1, hGSTK1
バックグラウンド:This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:GSTK1: Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB). Belongs to the GST superfamily. Kappa family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 2.5.1.18; Xenobiotic Metabolism - metabolism by cytochrome P450; Other Amino Acids Metabolism - glutathione; Transferase; Mitochondrial; Xenobiotic Metabolism - drug metabolism - cytochrome P450

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: membrane; intracellular membrane-bound organelle; mitochondrial matrix; mitochondrial inner membrane; peroxisome; intracellular

Molecular Function:glutathione transferase activity; protein disulfide oxidoreductase activity; glutathione peroxidase activity; receptor binding

Biological Process: glutathione metabolic process; epithelial cell differentiation

NCBI Summary:This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
UniProt Code:Q9Y2Q3
NCBI GenInfo Identifier:12643338
NCBI Gene ID:373156
NCBI Accession:Q9Y2Q3.3
UniProt Secondary Accession:Q9Y2Q3,Q6P4H0, Q7Z520, Q9P1S4, B4DIH1, B4DSY2,
UniProt Related Accession:Q9Y2Q3
Molecular Weight:226
NCBI Full Name:Glutathione S-transferase kappa 1
NCBI Synonym Full Names:glutathione S-transferase kappa 1
NCBI Official Symbol:GSTK1  
NCBI Official Synonym Symbols:GST; GST13; hGSTK1; GSTK1-1; GST13-13; GST 13-13  
NCBI Protein Information:glutathione S-transferase kappa 1; GST class-kappa; glutathione S-transferase k1; glutathione S-transferase subunit 13 homolog
UniProt Protein Name:Glutathione S-transferase kappa 1
UniProt Synonym Protein Names:GST 13-13; GST class-kappa; GSTK1-1; hGSTK1; Glutathione S-transferase subunit 13
Protein Family:Glutathione S-transferase
UniProt Gene Name:GSTK1  
UniProt Entry Name:GSTK1_HUMAN
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