Anti-GRPEL2 Antibody (CAB8339)
- SKU:
- CAB8339
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GRPEL2 Antibody |
| 抗体コード: | CAB8339 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-225 of human GRPEL2 (NP_689620.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-251MG, LO2, K-562, MCF7, Mouse liver, Mouse kidney, Mouse brain, Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-225 of human GRPEL2 (NP_689620.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | STAT QRTA GEDC RSED PPDE LGPP LAER ALRV KAVK LEKE VQDL TVRY QRAI ADCE NIRR RTQR CVED AKIF GIQS FCKD LVEV ADIL EKTT ECIS EESE PEDQ KLTL EKVF RGLL LLEA KLKS VFAK HGLE KLTP IGDK YDPH EHEL ICHV PAGV GVQP GTVA LVRQ DGYK LHGR TIRL ARVE VAVE SQRR L |
| 遺伝子ID: | 134266 |
| Uniprot: | Q8TAA5 |
| セルラーロケーション: | Mitochondrion matrix |
| 計算された分子量: | 14kDa/25kDa |
| 観察された分子量: | 20kDa |
| 同義語: | GRPEL2, Mt-GrpE#2, GrpE like 2 |
| バックグラウンド: |
| UniProt Protein Function: | GRPEL2: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70. Belongs to the GrpE family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 5q32 Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial inner membrane Molecular Function:protein homodimerization activity; adenyl-nucleotide exchange factor activity; chaperone binding; unfolded protein binding Biological Process: cellular protein metabolic process; protein folding; regulation of catalytic activity; protein targeting to mitochondrion |
| UniProt Code: | Q8TAA5 |
| NCBI GenInfo Identifier: | 22256760 |
| NCBI Gene ID: | 134266 |
| NCBI Accession: | Q8TAA5.1 |
| UniProt Secondary Accession: | Q8TAA5,Q49AJ6, B4DFA6, |
| UniProt Related Accession: | Q8TAA5 |
| Molecular Weight: | 14,277 Da |
| NCBI Full Name: | GrpE protein homolog 2, mitochondrial |
| NCBI Synonym Full Names: | GrpE-like 2, mitochondrial (E. coli) |
| NCBI Official Symbol: | GRPEL2 |
| NCBI Official Synonym Symbols: | Mt-GrpE#2 |
| NCBI Protein Information: | grpE protein homolog 2, mitochondrial |
| UniProt Protein Name: | GrpE protein homolog 2, mitochondrial |
| UniProt Synonym Protein Names: | Mt-GrpE#2 |
| Protein Family: | GrpE protein |
| UniProt Gene Name: | GRPEL2 |
| UniProt Entry Name: | GRPE2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GRPEL2 antibody (CAB8339) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat kidney using GRPEL2 Rabbit pAb (CAB8339) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human colon carcinoma using GRPEL2 Rabbit pAb (CAB8339) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using GRPEL2 Rabbit pAb (CAB8339) at dilution of 1:200 (40x lens). |
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