Anti-GRM5 Antibody (CAB3758)
- SKU:
- CAB3758
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GRM5 Antibody |
| 抗体コード: | CAB3758 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human GRM5 |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse brain |
| 免疫原: | A synthesized peptide derived from human GRM5 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 2915 |
| Uniprot: | P41594 |
| セルラーロケーション: | |
| 計算された分子量: | 132kDa |
| 観察された分子量: | 150kDa |
| 同義語: | GPRC1E, MGLUR5, PPP1R86, mGlu5 |
| バックグラウンド: | This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| UniProt Protein Function: | mGluR5: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol- calcium second messenger system and generates a calcium-activated chloride current. Belongs to the G-protein coupled receptor 3 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; GPCR, family 3; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 11q14.3 Cellular Component: integral to plasma membrane; plasma membrane; postsynaptic density Molecular Function:G-protein coupled receptor activity; glutamate receptor activity Biological Process: cognition; metabotropic glutamate receptor signaling pathway; metabotropic glutamate receptor, phospholipase C activating pathway; protein kinase C activation; regulation of synaptic transmission, glutamatergic; synaptic transmission |
| NCBI Summary: | This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| UniProt Code: | P41594 |
| NCBI GenInfo Identifier: | 1709020 |
| NCBI Gene ID: | 2915 |
| NCBI Accession: | P41594.2 |
| UniProt Secondary Accession: | P41594,Q6J164, |
| UniProt Related Accession: | P41594 |
| Molecular Weight: | 105,432 Da |
| NCBI Full Name: | Metabotropic glutamate receptor 5 |
| NCBI Synonym Full Names: | glutamate metabotropic receptor 5 |
| NCBI Official Symbol: | GRM5 |
| NCBI Official Synonym Symbols: | mGlu5; GPRC1E; MGLUR5; PPP1R86 |
| NCBI Protein Information: | metabotropic glutamate receptor 5 |
| UniProt Protein Name: | Metabotropic glutamate receptor 5 |
| Protein Family: | Metabotropic glutamate receptor |
| UniProt Gene Name: | GRM5 |
| UniProt Entry Name: | GRM5_HUMAN |
 | Western blot - GRM5 Rabbit mAb (CAB3758) |
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