Anti-GRIPAP1 Antibody (CAB12044)
- SKU:
- CAB12044
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GRIPAP1 Antibody |
| 抗体コード: | CAB12044 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 642-841 of human GRIPAP1 (NP_064522.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | U-87MG, HeLa, Jurkat, HepG2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 642-841 of human GRIPAP1 (NP_064522.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RSGL EELV LSEM NSPS RTQT GDSS SISS FSYR EILR EKES SAVP ARSL SSSP QAQP PRPA ELSD EEVA ELFQ RLAE TQQE KWML EEKV KHLE VSSA SMAE DLCR KSAI IETY VMDS RIDV SVAA GHTD RSGL GSVL RDLV KPGD ENLR EMNK KLQN MLEE QLTK NMHL HKDM EVLS QEIV RLSK ECVG PPDP DLEP GETS |
| 遺伝子ID: | 56850 |
| Uniprot: | Q4V328 |
| セルラーロケーション: | Early endosome |
| 計算された分子量: | 68kDa/71kDa/92kDa/95kDa |
| 観察された分子量: | 110kDa |
| 同義語: | GRIPAP1, GRASP-1 |
| バックグラウンド: | This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). The encoded protein interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA receptor function. |
| UniProt Protein Function: | GRIPAP1: a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). In brain studies, the encoded protein was found with the GRIP/AMPA receptor complex. Multiple alternatively spliced transcript variants have been described that encode different protein isoforms; however, the full-length nature and biological validity of all of these variants have not been determined.[provided by RefSeq, Nov 2009] |
| UniProt Protein Details: | Protein type:GEF; GEF, Ras Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: cytosol; intracellular membrane-bound organelle; nucleoplasm Molecular Function:protein binding |
| NCBI Summary: | This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). The encoded protein interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA receptor function. [provided by RefSeq, Aug 2013] |
| UniProt Code: | Q4V328 |
| NCBI GenInfo Identifier: | 74753569 |
| NCBI Gene ID: | 56850 |
| NCBI Accession: | Q4V328.1 |
| UniProt Secondary Accession: | Q4V328,Q3MJ75, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8 Q9NQ43, Q9ULQ3, A6NL78, |
| UniProt Related Accession: | Q4V328 |
| Molecular Weight: | 96kDa |
| NCBI Full Name: | GRIP1-associated protein 1 |
| NCBI Synonym Full Names: | GRIP1 associated protein 1 |
| NCBI Official Symbol: | GRIPAP1 |
| NCBI Official Synonym Symbols: | GRASP-1 |
| NCBI Protein Information: | GRIP1-associated protein 1 |
| UniProt Protein Name: | GRIP1-associated protein 1 |
| Protein Family: | GRIP1-associated protein |
| UniProt Gene Name: | GRIPAP1 |
 | Western blot analysis of extracts of various cell lines, using GRIPAP1 antibody (CAB12044) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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