Anti-GPS2 Antibody (CAB3901)
- SKU:
- CAB3901
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-GPS2 Antibody |
| 抗体コード: | CAB3901 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IP |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of mouse GPS2 (NP_062700.2). |
| 申し込み: | WB IP |
| 推奨希釈: | WB 1:500 - 1:2000 IP 1:20 - 1:50 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, SKOV3, A-431, SGC-7901, BxPC-3, Mouse lung, Mouse testis, Rat testis |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of mouse GPS2 (NP_062700.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TQPA YSPS QQLR APSA FPAV QYLS QPQP QPYA VHGH FQPT QTGF LQPG STLS LQKQ MEHA NQQT SFSD SSSL RPMH PQAL HPAP GLLA SPQL PVQI QAAG KSGF ATTS QPGP RLPF IQHS QNPR FYHK |
| 遺伝子ID: | 56310 |
| Uniprot: | |
| セルラーロケーション: | |
| 計算された分子量: | 20kDa |
| 観察された分子量: | 37kDa |
| 同義語: | GPS2, AMF-1 |
| バックグラウンド: | This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. |