Anti-GPR78 Antibody (CAB12364)
- SKU:
- CAB12364
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GPR78 Antibody |
| 抗体コード: | CAB12364 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 294-363 of human GPR78 (NP_543009.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse liver, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 294-363 of human GPR78 (NP_543009.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | YSLL RRPF RQVL AGMV HRLL KRTP RPAS THDS SLDV AGMV HQLL KRTP RPAS THNG SVDT ENDS CLQQ TH |
| 遺伝子ID: | 27201 |
| Uniprot: | Q96P69 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 39kDa |
| 観察された分子量: | 39kDa |
| 同義語: | GPR78 |
| バックグラウンド: | The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | GPR78: Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 4p16.1 Molecular Function:G-protein coupled receptor activity Biological Process: G-protein signaling, adenylate cyclase activating pathway |
| NCBI Summary: | The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011] |
| UniProt Code: | Q96P69 |
| NCBI GenInfo Identifier: | 46397876 |
| NCBI Gene ID: | 27201 |
| NCBI Accession: | Q96P69.2 |
| UniProt Secondary Accession: | Q96P69,Q8NGV3, |
| UniProt Related Accession: | Q96P69 |
| Molecular Weight: | 39,332 Da |
| NCBI Full Name: | G-protein coupled receptor 78 |
| NCBI Synonym Full Names: | G protein-coupled receptor 78 |
| NCBI Official Symbol: | GPR78 |
| NCBI Protein Information: | G-protein coupled receptor 78 |
| UniProt Protein Name: | G-protein coupled receptor 78 |
| Protein Family: | G-protein coupled receptor |
| UniProt Gene Name: | GPR78 |
| UniProt Entry Name: | GPR78_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GPR78 antibody (CAB12364) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human placenta using GPR78 antibody (CAB12364) at dilution of 1:100 (40x lens). |
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