Anti-GPR37 Antibody (CAB16724)
- SKU:
- CAB16724
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GPR37 Antibody |
| 抗体コード: | CAB16724 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-180 of human GPR37 (NP_005293.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Rat |
| ポジティブサンプル: | U-87MG, U-251MG |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-180 of human GPR37 (NP_005293.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LGES CAPT VIQR RGRD AWGP GNSA RDVL RARA PREE QGAA FLAG PSWD LPAA PGRD PAAG RGAE ASAA GPPG PPTR PPGP WRWK GARG QEPS ETLG RGNP TALQ LFLQ ISEE EEKG PRGA GISG RSQE QSVK TVPG ASDL F |
| 遺伝子ID: | 2861 |
| Uniprot: | O15354 |
| セルラーロケーション: | |
| 計算された分子量: | 67kDa |
| 観察された分子量: | 67kDa |
| 同義語: | GPR37, EDNRBL, PAELR, hET(B)R-LP |
| バックグラウンド: | This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease. |
| UniProt Protein Function: | GPR37: Orphan receptor. May have a unique functional role in the central nervous system. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1 Chromosomal Location of Human Ortholog: 7q31 Cellular Component: endoplasmic reticulum membrane; integral to plasma membrane; plasma membrane; ubiquitin ligase complex; receptor complex Molecular Function:G-protein coupled receptor activity; protein binding; ubiquitin protein ligase binding; heat shock protein binding; peptide receptor activity, G-protein coupled; Hsp70 protein binding; peptide binding Biological Process: positive regulation of dopamine metabolic process; G-protein coupled receptor protein signaling pathway; positive regulation of MAPKKK cascade; dopamine biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; locomotion during locomotory behavior |
| NCBI Summary: | This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease. [provided by RefSeq, Oct 2012] |
| UniProt Code: | O15354 |
| NCBI GenInfo Identifier: | 4885323 |
| NCBI Gene ID: | 2861 |
| NCBI Accession: | NP_005293.1 |
| UniProt Secondary Accession: | O15354,O00348, O14768, Q8TD39, |
| UniProt Related Accession: | O15354 |
| Molecular Weight: | 67,114 Da |
| NCBI Full Name: | probable G-protein coupled receptor 37 |
| NCBI Synonym Full Names: | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| NCBI Official Symbol: | GPR37 |
| NCBI Official Synonym Symbols: | PAELR; EDNRBL; hET(B)R-LP |
| NCBI Protein Information: | probable G-protein coupled receptor 37; ETBR-LP-1; endothelin B receptor-like protein 1; Parkin-associated endothelin receptor-like receptor |
| UniProt Protein Name: | Probable G-protein coupled receptor 37 |
| UniProt Synonym Protein Names: | Endothelin B receptor-like protein 1; ETBR-LP-1; Parkin-associated endothelin receptor-like receptor |
| Protein Family: | Prosaposin receptor |
| UniProt Gene Name: | GPR37 |
| UniProt Entry Name: | GPR37_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GPR37 antibody (CAB16724) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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