| UniProt Protein Function: | Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. |
| NCBI Summary: | This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.[provided by RefSeq, Jan 2010] |
| UniProt Code: | Q8TDV5 |
| NCBI GenInfo Identifier: | 30425400 |
| NCBI Gene ID: | 139760 |
| NCBI Accession: | NP_848566.1 |
| UniProt Secondary Accession: | Q8TDV5,Q495H7, Q4VBN3, |
| UniProt Related Accession: | Q8TDV5 |
| Molecular Weight: | 36,889 Da |
| NCBI Full Name: | glucose-dependent insulinotropic receptor |
| NCBI Synonym Full Names: | G protein-coupled receptor 119 |
| NCBI Official Symbol: | GPR119 |
| NCBI Official Synonym Symbols: | GPCR2 |
| NCBI Protein Information: | glucose-dependent insulinotropic receptor |
| UniProt Protein Name: | Glucose-dependent insulinotropic receptor |
| UniProt Synonym Protein Names: | G-protein coupled receptor 119 |
| Protein Family: | Gastric inhibitory polypeptide receptor |
| UniProt Gene Name: | GPR119 |
