Anti-GNGT1 Antibody (CAB15675)
- SKU:
- CAB15675
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GNGT1 Antibody |
| 抗体コード: | CAB15675 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-45 of human GNGT1 (NP_068774.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse eye, Rat eye |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-45 of human GNGT1 (NP_068774.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MPVI NIED LTEK DKLK MEVD QLKK EVTL ERML VSKC CEEV RDYV E |
| 遺伝子ID: | 2792 |
| Uniprot: | P63211 |
| セルラーロケーション: | Cell membrane, Cytoplasmic side, Lipid-anchor |
| 計算された分子量: | 8kDa |
| 観察された分子量: | 10kDa |
| 同義語: | GNGT1, GNG1 |
| バックグラウンド: | This gene encodes the gamma subunit of transducin, a guanine nucleotide-binding protein (G protein) that is found in rod outer segments. Transducin, also known as GMPase, mediates the activation of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase by rhodopsin. |
| UniProt Protein Function: | G-gamma t1: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family. |
| UniProt Protein Details: | Protein type:G protein; G protein, heterotrimeric gamma; G protein, heterotrimeric Chromosomal Location of Human Ortholog: 7q21.3 Cellular Component: plasma membrane Molecular Function:GTPase activity; protein binding Biological Process: regulation of rhodopsin mediated signaling; rhodopsin mediated signaling |
| NCBI Summary: | This gene encodes the gamma subunit of transducin, a guanine nucleotide-binding protein (G protein) that is found in rod outer segments. Transducin, also known as GMPase, mediates the activation of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase by rhodopsin. [provided by RefSeq, Jul 2016] |
| UniProt Code: | P63211 |
| NCBI GenInfo Identifier: | 52783592 |
| NCBI Gene ID: | 2792 |
| NCBI Accession: | P63211.2 |
| UniProt Secondary Accession: | P63211,O43835, Q08447, Q16026, Q6LCP6, A4D1H2, |
| UniProt Related Accession: | P63211 |
| Molecular Weight: | 8,496 Da |
| NCBI Full Name: | Guanine nucleotide-binding protein G(T) subunit gamma-T1 |
| NCBI Synonym Full Names: | G protein subunit gamma transducin 1 |
| NCBI Official Symbol: | GNGT1 |
| NCBI Official Synonym Symbols: | GNG1 |
| NCBI Protein Information: | guanine nucleotide-binding protein G(T) subunit gamma-T1 |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(T) subunit gamma-T1 |
| UniProt Synonym Protein Names: | Transducin gamma chain |
| UniProt Gene Name: | GNGT1 |
| UniProt Entry Name: | GBG1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GNGT1 antibody (CAB15675) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of rat eye using GNGT1 Polyclonal Antibody (CAB15675) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of mouse eye using GNGT1 Polyclonal Antibody (CAB15675) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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