Anti-GNG3 Antibody (CAB9817)
- SKU:
- CAB9817
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GNG3 Antibody |
| 抗体コード: | CAB9817 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human GNG3 (NP_036334.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human GNG3 (NP_036334.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MKGE TPVN STMS IGQA RKMV EQLK IEAS LCRI KVSK AAAD LMTY CDAH ACED PLIT PVPT SENP FREK KFFC ALL |
| 遺伝子ID: | 2785 |
| Uniprot: | P63215 |
| セルラーロケーション: | Cell membrane, Cytoplasmic side, Lipid-anchor |
| 計算された分子量: | 8kDa |
| 観察された分子量: | 14kDa |
| 同義語: | GNG3 |
| バックグラウンド: | Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The gamma subunit determines the specificity of which signaling pathways will be affected by this particular complex. The protein encoded by this gene represents the gamma subunit of both inhibitory and stimulatory complexes. |
| UniProt Protein Function: | G-gamma 3: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family. |
| UniProt Protein Details: | Protein type:G protein, heterotrimeric gamma; G protein, heterotrimeric; G protein Chromosomal Location of Human Ortholog: 11p11 Cellular Component: plasma membrane Molecular Function:GTPase activity Biological Process: activation of MAPK activity |
| NCBI Summary: | Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The gamma subunit determines the specificity of which signaling pathways will be affected by this particular complex. The protein encoded by this gene represents the gamma subunit of both inhibitory and stimulatory complexes. [provided by RefSeq, Jan 2012] |
| UniProt Code: | P63215 |
| NCBI GenInfo Identifier: | 52783596 |
| NCBI Gene ID: | 2785 |
| NCBI Accession: | P63215.1 |
| UniProt Secondary Accession: | P63215,P29798, Q61014, B2R4S7, |
| UniProt Related Accession: | P63215 |
| Molecular Weight: | 8,305 Da |
| NCBI Full Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 |
| NCBI Synonym Full Names: | G protein subunit gamma 3 |
| NCBI Official Symbol: | GNG3 |
| NCBI Protein Information: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 |
| UniProt Gene Name: | GNG3 |
| UniProt Entry Name: | GBG3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GNG3 antibody (CAB9817) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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