Anti-GMPPB Antibody (CAB16520)

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SKU:
CAB16520
Product type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-GMPPB Antibody
抗体コード:CAB16520
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Mouse
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 50-250 of human GMPPB (NP_068806.1).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Mouse
ポジティブサンプル:Mouse thymus, Mouse brain
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 50-250 of human GMPPB (NP_068806.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:ILAV SYMS QVLE KEMK AQEQ RLGI RISM SHEE EPLG TAGP LALA RDLL SETA DPFF VLNS DVIC DFPF QAMV QFHR HHGQ EGSI LVTK VEEP SKYG VVVC EADT GRIH RFVE KPQV FVSN KINA GMYI LSPA VLRR IQLQ PTSI EKEV FPIM AKEG QLYA MELQ GFWM DIGQ PKDF LTGM CLFL QSLR QKQP ERLC SGPG I
遺伝子ID:29925
Uniprot:Q9Y5P6
セルラーロケーション:Cytoplasm
計算された分子量:39kDa/42kDa
観察された分子量:41kDa
同義語:GMPPB, MDDGA14, MDDGB14, MDDGC14
バックグラウンド:This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described.
UniProt Protein Function:GMPPB: This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2009]
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 2.7.7.13; Carbohydrate Metabolism - fructose and mannose; Transferase

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: cytoplasm

Molecular Function:protein binding

Disease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 14; Muscular Dystrophy-dystroglycanopathy (congenital With Mental Retardation), Type B, 14; Muscular Dystrophy-dystroglycanopathy (limb-girdle), Type C, 14

NCBI Summary:This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2009]
UniProt Code:Q9Y5P6
NCBI GenInfo Identifier:160013885
NCBI Gene ID:29925
NCBI Accession:Q9Y5P6.2
UniProt Secondary Accession:Q9Y5P6,Q9H7U3, A8K6N5,
UniProt Related Accession:Q9Y5P6
Molecular Weight:42,622 Da
NCBI Full Name:Mannose-1-phosphate guanyltransferase beta
NCBI Synonym Full Names:GDP-mannose pyrophosphorylase B
NCBI Official Symbol:GMPPB  
NCBI Official Synonym Symbols:MDDGA14; MDDGB14; MDDGC14  
NCBI Protein Information:mannose-1-phosphate guanyltransferase beta
UniProt Protein Name:Mannose-1-phosphate guanyltransferase beta
UniProt Synonym Protein Names:GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta
Protein Family:Mannose-1-phosphate guanyltransferase
UniProt Gene Name:GMPPB  
UniProt Entry Name:GMPPB_HUMAN
Anti-GMPPB Antibody (CAB16520)Western blot analysis of extracts of various cell lines, using GMPPB antibody (CAB16520) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 10s.
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