Anti-GLYR1 Antibody (CAB9046)
- SKU:
- CAB9046
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GLYR1 Antibody |
| 抗体コード: | CAB9046 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-270 of human GLYR1 (NP_115958.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, Mouse brain, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-270 of human GLYR1 (NP_115958.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MIKI NKGK RFQQ AVDA VEEF LRRA KGKD QTSS HNSS DDKN RRNS SEER SRPN SGDE KRKL SLSE GKVK KNMG EGKK RVSS GSSE RGSK SPLK RAQE QSPR KRGR PPKD EKDL TIPE SSTV KGMM AGPM AAFK WQPT ASEP VKDA DPHF HHFL LSQT EKPA VCYQ AITK KLKI CEEE TGST SIQA ADST AVNG SITP TDKK I |
| 遺伝子ID: | 84656 |
| Uniprot: | Q49A26 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 51kDa/52kDa/58kDa/59kDa/60kDa |
| 観察された分子量: | 60kDa |
| 同義語: | GLYR1, BM045, HIBDL, N-PAC, NP60 |
| バックグラウンド: |
| UniProt Protein Function: | Putative oxidoreductase that is recruited on chromatin and promotes KDM1B demethylase activity (PubMed:23260659). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3) (PubMed:20850016). Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling (PubMed:16352664). Indirectly promotes phosphorylation of MAPK14 and activation of ATF2 (PubMed:16352664). The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6 (PubMed:16352664). |
| UniProt Code: | Q49A26 |
| NCBI GenInfo Identifier: | 862669336 |
| NCBI Gene ID: | 84656 |
| NCBI Accession: | NP_001295025.1 |
| UniProt Secondary Accession: | Q49A26,Q5U632, Q6P1Q2, Q6V3W7, Q9BTI1, Q9BXK2, B4DL47 C9JJ40, C9JJ60, |
| UniProt Related Accession: | Q49A26 |
| Molecular Weight: | 52,559 Da |
| NCBI Full Name: | putative oxidoreductase GLYR1 isoform 2 |
| NCBI Synonym Full Names: | glyoxylate reductase 1 homolog |
| NCBI Official Symbol: | GLYR1 |
| NCBI Official Synonym Symbols: | NP60; BM045; HIBDL; N-PAC |
| NCBI Protein Information: | putative oxidoreductase GLYR1 |
| UniProt Protein Name: | Putative oxidoreductase GLYR1 |
| UniProt Synonym Protein Names: | 3-hydroxyisobutyrate dehydrogenase-like protein; Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1 homolog; Nuclear protein NP60; Nuclear protein of 60 kDa |
| UniProt Gene Name: | GLYR1 |
 | Western blot analysis of extracts of various cell lines, using GLYR1 antibody (CAB9046) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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