Anti-GJD2 Antibody (CAB2883)
- SKU:
- CAB2883
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-GJD2 Antibody |
抗体コード: | CAB2883 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 99-197 of human GJD2 (NP_065711.1). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HL-60, Jurkat, SH-SY5Y, Mouse pancreas, Mouse eye, Mouse brain, Rat pancreas, Rat eye, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 99-197 of human GJD2 (NP_065711.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | HQSA KQRE RRYS TVFL ALDR DPPE SIGG PGGT GGGG SGGG KRED KKLQ NAIV NGVL QNTE NTSK ETEP DCLE VKEL TPHP SGLR TASK SKLR RQEG ISR |
遺伝子ID: | 57369 |
Uniprot: | Q9UKL4 |
セルラーロケーション: | Cell junction, Cell membrane, Multi-pass membrane protein, gap junction |
計算された分子量: | 36kDa |
観察された分子量: | 37kDa |
同義語: | GJD2, CX36, GJA9 |
バックグラウンド: | This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion. |
UniProt Protein Function: | GJD2: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Delta-type subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Cell adhesion; Membrane protein, integral; Channel, misc. Chromosomal Location of Human Ortholog: 15q14 Cellular Component: connexon complex; plasma membrane; integral to membrane Molecular Function:gap junction channel activity Biological Process: synaptic transmission; regulation of action potential; visual perception; transmembrane transport |
NCBI Summary: | This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion. [provided by RefSeq, Oct 2012] |
UniProt Code: | Q9UKL4 |
NCBI GenInfo Identifier: | 8928073 |
NCBI Gene ID: | 57369 |
NCBI Accession: | Q9UKL4.1 |
UniProt Secondary Accession: | Q9UKL4,O70610, O54851, Q866T7, |
UniProt Related Accession: | Q9UKL4 |
Molecular Weight: | 321 |
NCBI Full Name: | Gap junction delta-2 protein |
NCBI Synonym Full Names: | gap junction protein, delta 2, 36kDa |
NCBI Official Symbol: | GJD2 |
NCBI Official Synonym Symbols: | CX36; GJA9 |
NCBI Protein Information: | gap junction delta-2 protein; connexin 36; connexin-36; gap junction alpha-9 protein |
UniProt Protein Name: | Gap junction delta-2 protein |
UniProt Synonym Protein Names: | Connexin-36; Cx36; Gap junction alpha-9 protein |
UniProt Gene Name: | GJD2 |
UniProt Entry Name: | CXD2_HUMAN |
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