Anti-GJC1 Antibody (CAB7053)
- SKU:
- CAB7053
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GJC1 Antibody |
| 抗体コード: | CAB7053 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 247-396 of human GJC1 (NP_005488.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | SW480, 293T, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 247-396 of human GJC1 (NP_005488.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | IWEM LHLG FGTI RDSL NSKR RELE DPGA YNYP FTWN TPSA PPGY NIAV KPDQ IQYT ELSN AKIA YKQN KANT AQEQ QYGS HEEN LPAD LEAL QREI RMAQ ERLD LAVQ AYSH QNNP HGPR EKKA KVGS KAGS NKST ASSK SGDG KTSV WI |
| 遺伝子ID: | 10052 |
| Uniprot: | P36383 |
| セルラーロケーション: | Cell junction, Cell membrane, Multi-pass membrane protein, gap junction |
| 計算された分子量: | 45kDa |
| 観察された分子量: | 45kDa |
| 同義語: | GJC1, CX45, GJA7 |
| バックグラウンド: | This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. |
| UniProt Protein Function: | GJC1: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 17q21.31 Cellular Component: connexon complex; endoplasmic reticulum membrane; plasma membrane; gap junction; integral to membrane Molecular Function:ion channel activity; gap junction channel activity Biological Process: cardiac muscle development; intercellular junction assembly; synaptic transmission; gap junction assembly; visual perception; muscle contraction; transport; vasculogenesis; cell development |
| NCBI Summary: | This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P36383 |
| NCBI GenInfo Identifier: | 226693517 |
| NCBI Gene ID: | 10052 |
| NCBI Accession: | P36383.2 |
| UniProt Secondary Accession: | P36383,Q4VAY0, B3KW68, |
| UniProt Related Accession: | P36383 |
| Molecular Weight: | 45,470 Da |
| NCBI Full Name: | Gap junction gamma-1 protein |
| NCBI Synonym Full Names: | gap junction protein, gamma 1, 45kDa |
| NCBI Official Symbol: | GJC1 |
| NCBI Official Synonym Symbols: | CX45; GJA7 |
| NCBI Protein Information: | gap junction gamma-1 protein; connexin 45; connexin-45; gap junction alpha-7 protein |
| UniProt Protein Name: | Gap junction gamma-1 protein |
| UniProt Synonym Protein Names: | Connexin-45; Cx45; Gap junction alpha-7 protein |
| Protein Family: | Gap junction gamma-1 protein |
| UniProt Gene Name: | GJC1 |
| UniProt Entry Name: | CXG1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GJC1 antibody (CAB7053) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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