Anti-GJA4 Antibody (CAB2529)
- SKU:
- CAB2529
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GJA4 Antibody |
| 抗体コード: | CAB2529 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 229-333 of human GJA4 (NP_002051.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | SW620, BT-474, 293T, NCI-H460 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 229-333 of human GJA4 (NP_002051.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VHLL CRCL SRGM RARQ GQDA PPTQ GTSS DPYT DQVF FYLP VGQG PSSP PCPT YNGL SSSE QNWA NLTT EERL ASSR PPLF LDPP PQNG QKPP SRPS SSAS KKQY V |
| 遺伝子ID: | 2701 |
| Uniprot: | P35212 |
| セルラーロケーション: | Cell junction, Cell membrane, Multi-pass membrane protein, gap junction |
| 計算された分子量: | 37kDa |
| 観察された分子量: | 43kDa |
| 同義語: | GJA4, CX37 |
| バックグラウンド: | This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. |
| UniProt Protein Function: | GJA4: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Alpha-type (group II) subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1p35.1 Cellular Component: connexon complex; integral to plasma membrane; gap junction Molecular Function:protein binding Biological Process: intercellular junction assembly; blood vessel development; cell-cell signaling; transport; calcium ion transport; response to pain |
| NCBI Summary: | This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P35212 |
| NCBI GenInfo Identifier: | 8928555 |
| NCBI Gene ID: | 2701 |
| NCBI Accession: | P35212.3 |
| UniProt Secondary Accession: | P35212,Q9P106, Q9UBL1, Q9UNA9, Q9UNB0, Q9UNB1, Q9Y5N7 A8K698, D3DPR4, |
| UniProt Related Accession: | P35212 |
| Molecular Weight: | |
| NCBI Full Name: | Gap junction alpha-4 protein |
| NCBI Synonym Full Names: | gap junction protein, alpha 4, 37kDa |
| NCBI Official Symbol: | GJA4 |
| NCBI Official Synonym Symbols: | CX37 |
| NCBI Protein Information: | gap junction alpha-4 protein; connexin 37; connexin-37 |
| UniProt Protein Name: | Gap junction alpha-4 protein |
| UniProt Synonym Protein Names: | Connexin-37; Cx37 |
| Protein Family: | Gap junction alpha-4 protein |
| UniProt Gene Name: | GJA4 |
| UniProt Entry Name: | CXA4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GJA4 antibody (CAB2529) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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