| 同義語: | GIPC1, C19orf3, GIPC, GLUT1CBP, Hs.6454, IIP-1, NIP, RGS19IP1, SEMCAP, SYNECTIIN, SYNECTIN, TIP-2 |
| UniProt Protein Function: | GIPC1: May be involved in G protein-linked signaling. Belongs to the GIPC family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:GAP; GAP, misc.; Motility/polarity/chemotaxis; Vesicle Chromosomal Location of Human Ortholog: 19p13.12 Cellular Component: cell cortex; cytoplasm; cytoplasmic vesicle; cytosol; dendritic shaft; dendritic spine; membrane; synaptic vesicle; vesicle membrane Molecular Function:actin binding; cadherin binding; myosin binding; protein binding; protein homodimerization activity; receptor binding Biological Process: endothelial cell migration; glutamate secretion; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cytokinesis; positive regulation of transforming growth factor beta receptor signaling pathway; protein targeting; regulation of protein stability; regulation of synaptic plasticity; synaptic transmission |
| NCBI Summary: | GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009] |
| UniProt Code: | O14908 |
| NCBI GenInfo Identifier: | 17375873 |
| NCBI Gene ID: | 10755 |
| NCBI Accession: | O14908.2 |
| UniProt Secondary Accession: | O14908,Q9BTC9, A8K4I3, A8MZG3, |
| UniProt Related Accession: | O14908 |
| Molecular Weight: | 36kDa |
| NCBI Full Name: | PDZ domain-containing protein GIPC1 |
| NCBI Synonym Full Names: | GIPC PDZ domain containing family member 1 |
| NCBI Official Symbol: | GIPC1 |
| NCBI Official Synonym Symbols: | NIP; GIPC; IIP-1; TIP-2; SEMCAP; C19orf3; Hs.6454; GLUT1CBP; RGS19IP1; SYNECTIN; SYNECTIIN |
| NCBI Protein Information: | PDZ domain-containing protein GIPC1 |
| UniProt Protein Name: | PDZ domain-containing protein GIPC1 |
| UniProt Synonym Protein Names: | GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; RGS19-interacting protein 1; Synectin; Tax interaction protein 2; TIP-2 |
| Protein Family: | PDZ domain-containing protein |
| UniProt Gene Name: | GIPC1 |
