Anti-GIMAP5 Antibody (CAB8684)
- SKU:
- CAB8684
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GIMAP5 Antibody |
| 抗体コード: | CAB8684 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-270 of human GIMAP5 (NP_060854.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse kidney, Rat spleen |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-270 of human GIMAP5 (NP_060854.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | WGSV EEQR QQQA ELLA VIER LGRE REGS FHSN DLFL DAQL LQRT GAGA CQED YRQY QAKV EWQV EKHK QELR ENES NWAY K |
| 遺伝子ID: | 55340 |
| Uniprot: | Q96F15 |
| セルラーロケーション: | Lysosome, Mitochondrion outer membrane, Single-pass type IV membrane protein |
| 計算された分子量: | 34kDa/39kDa |
| 観察された分子量: | 34kDa |
| 同義語: | GIMAP5, HIMAP3, IAN-5, IAN4, IAN4L1, IAN5, IMAP3, IROD |
| バックグラウンド: | This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. |
| UniProt Protein Function: | GIMAP5: Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence. Belongs to the IAN GTP-binding protein family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Hydrolase; Apoptosis; Mitochondrial; Membrane protein, integral Chromosomal Location of Human Ortholog: 7q36.1 Cellular Component: mitochondrial outer membrane; lysosome; integral to membrane Molecular Function:GTP binding |
| NCBI Summary: | This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. [provided by RefSeq, Dec 2010] |
| UniProt Code: | Q96F15 |
| NCBI GenInfo Identifier: | 28416949 |
| NCBI Gene ID: | 55340 |
| NCBI Accession: | NP_060854.2 |
| UniProt Secondary Accession: | Q96F15,Q6IA75, Q96NE4, Q9NUK9, D3DWZ5, |
| UniProt Related Accession: | Q96F15 |
| Molecular Weight: | 34,846 Da |
| NCBI Full Name: | GTPase IMAP family member 5 |
| NCBI Synonym Full Names: | GTPase, IMAP family member 5 |
| NCBI Official Symbol: | GIMAP5 |
| NCBI Official Synonym Symbols: | IAN4; IAN5; IROD; IAN-5; IMAP3; HIMAP3; IAN4L1 |
| NCBI Protein Information: | GTPase IMAP family member 5; immunity associated protein 3; immune associated nucleotide 4 like 1; immunity-associated nucleotide 5 protein; inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5 |
| UniProt Protein Name: | GTPase IMAP family member 5 |
| UniProt Synonym Protein Names: | Immunity-associated nucleotide 4-like 1 protein; Immunity-associated nucleotide 5 protein; IAN-5; hIAN5; Immunity-associated protein 3 |
| Protein Family: | GTPase IMAP family |
| UniProt Gene Name: | GIMAP5 |
| UniProt Entry Name: | GIMA5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GIMAP5 antibody (CAB8684) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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