Anti-GFRA3 Antibody (CAB2955)
- SKU:
- CAB2955
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GFRA3 Antibody |
| 抗体コード: | CAB2955 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-240 of human GFRA3 (NP_001487.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | A-549, BxPC-3, HepG2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-240 of human GFRA3 (NP_001487.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DPLP TESR LMNS CLQA RRKC QADP TCSA AYHH LDSC TSSI STPL PSEE PSVP ADCL EAAQ QLRN SSLI GCMC HRRM KNQV ACLD IYWT VHRA RSLG NYEL DVSP YEDT VTSK PWKM NLSK LNML KPDS DLCL KFAM LCTL NDKC DRLR KAYG EACS GPHC QRHV CLRQ LLTF FEKA AEPH AQGL LLCP CAPN DRGC GERR RNTI APNC A |
| 遺伝子ID: | 2676 |
| Uniprot: | O60609 |
| セルラーロケーション: | Cell membrane, GPI-anchor, Lipid-anchor |
| 計算された分子量: | 40kDa/44kDa |
| 観察された分子量: | 45kDa |
| 同義語: | GFRA3, GDNFR3 |
| バックグラウンド: | The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. |
| UniProt Protein Function: | GFRA3: Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase. Belongs to the GDNFR family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 5q31.1-q31.3 Cellular Component: extrinsic to membrane; intracellular membrane-bound organelle; cytoplasm; plasma membrane; external side of plasma membrane Molecular Function:axon guidance receptor activity; receptor binding Biological Process: axon guidance; nervous system development; sympathetic nervous system development; neuron migration; signal transduction; peripheral nervous system development |
| NCBI Summary: | The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60609 |
| NCBI GenInfo Identifier: | 50403696 |
| NCBI Gene ID: | 2676 |
| NCBI Accession: | O60609.2 |
| UniProt Related Accession: | O60609 |
| Molecular Weight: | Observed Molecular Weight: (Observed)44kD.Predicted Molecular Weight: (Calculated)45kDa. |
| NCBI Full Name: | GDNF family receptor alpha-3 |
| NCBI Synonym Full Names: | GDNF family receptor alpha 3 |
| NCBI Official Symbol: | GFRA3 |
| NCBI Official Synonym Symbols: | GDNFR3 |
| NCBI Protein Information: | GDNF family receptor alpha-3 |
| UniProt Protein Name: | GDNF family receptor alpha-3 |
| Protein Family: | GDNF family receptor |
| UniProt Gene Name: | GFRA3 |
| UniProt Entry Name: | GFRA3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GFRA3 antibody (CAB2955) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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