Anti-GFI1 Antibody (CAB16862)
- SKU:
- CAB16862
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-GFI1 Antibody |
| 抗体コード: | CAB16862 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GFI1 (NP_001120687.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse spleen, Rat thymus, Rat spleen |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GFI1 (NP_001120687.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MPRS FLVK SKKA HSYH QPRS PGPD YSLR LENV PAPS RADS TSNA GGAK AEPR DRLS PESQ LTEA PDRA SASP DSCE GSVC ERSS EFED FWRP PSPS ASPA |
| 遺伝子ID: | 2672 |
| Uniprot: | Q99684 |
| セルラーロケーション: | |
| 計算された分子量: | 45kDa |
| 観察された分子量: | 45kDa |
 | Western blot - GFI1 Rabbit pAb (CAB16862) |
| 同義語: | GFI1, GFI-1, GFI1A, SCN2, ZNF163 |
| バックグラウンド: | This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. |
| NCBI Summary: | This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99684 |
| NCBI GenInfo Identifier: | 33860154 |
| NCBI Gene ID: | 2672 |
| NCBI Accession: | Q99684.2 |
| UniProt Related Accession: | Q99684 |
| Molecular Weight: | |
| NCBI Full Name: | Zinc finger protein Gfi-1 |
| NCBI Synonym Full Names: | growth factor independent 1 transcriptional repressor |
| NCBI Official Symbol: | GFI1 |
| NCBI Official Synonym Symbols: | SCN2; GFI-1; GFI1A; ZNF163 |
| NCBI Protein Information: | zinc finger protein Gfi-1 |
| UniProt Protein Name: | Zinc finger protein Gfi-1 |
| UniProt Synonym Protein Names: | Growth factor independent protein 1; Zinc finger protein 163 |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | GFI1 |
| UniProt Entry Name: | GFI1_HUMAN |