Anti-GEMIN6 Antibody (CAB12375)
- SKU:
- CAB12375
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-GEMIN6 Antibody |
抗体コード: | CAB12375 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human GEMIN6 (NP_079051.9). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HT-29, HeLa, 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human GEMIN6 (NP_079051.9). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSEW MKKG PLEW QDYI YKEV RVTA SEKN EYKG WVLT TDPV SANI VLVN FLED GSMS VTGI MGHA VQTV ETMN EGDH RVRE KLMH LFTS GDCK AYSP EDLE ERKN SLKK WLEK NHIP ITEQ GDAP RTLC VAGV LTID PPYG PENC SSSN EIIL SRVQ DLIE GHLT ASQ |
遺伝子ID: | 79833 |
Uniprot: | Q8WXD5 |
セルラーロケーション: | Cytoplasm, Nucleus, gem, nucleoplasm |
計算された分子量: | 18kDa |
観察された分子量: | 19kDa |
同義語: | GEMIN6 |
バックグラウンド: |
UniProt Protein Function: | GEMIN6: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. |
UniProt Protein Details: | Protein type:RNA splicing Chromosomal Location of Human Ortholog: 2p22.1 Cellular Component: cytoplasm; cytosol; nuclear body; nucleoplasm; SMN complex Molecular Function:protein binding Biological Process: nuclear import; nuclear mRNA splicing, via spliceosome; spliceosomal snRNP biogenesis |
NCBI Summary: | GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).[supplied by OMIM, Jul 2002] |
UniProt Code: | Q8WXD5 |
NCBI GenInfo Identifier: | 34921901 |
NCBI Gene ID: | 79833 |
NCBI Accession: | Q8WXD5.1 |
UniProt Secondary Accession: | Q8WXD5,Q53SI5, Q8WVB4, Q9H5G6, B2RDP8, |
UniProt Related Accession: | Q8WXD5 |
Molecular Weight: | 19kDa |
NCBI Full Name: | Gem-associated protein 6 |
NCBI Synonym Full Names: | gem nuclear organelle associated protein 6 |
NCBI Official Symbol: | GEMIN6 |
NCBI Protein Information: | gem-associated protein 6 |
UniProt Protein Name: | Gem-associated protein 6 |
UniProt Synonym Protein Names: | SIP2 |
Protein Family: | Gem-associated protein |
UniProt Gene Name: | GEMIN6 |
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