Anti-GEMIN4 Antibody (CAB10764)
- SKU:
- CAB10764
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-GEMIN4 Antibody |
抗体コード: | CAB10764 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-350 of human GEMIN4 (NP_056536.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | HeLa, MCF7, SH-SY5Y, Jurkat, Mouse brain, Mouse kidney, Mouse liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-350 of human GEMIN4 (NP_056536.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LREI SSAA AHSQ PFAW KKKA LIII WAKV LQPH PVTP SDTE TRWQ EDLF FSVG NMIP TINH TILF ELLK SLEA SGLF IQLL MALP TTIC HAEL ERFL EHVT VDTS AEDV AFFL DVWW EVMK HKGH PQDP LLSQ FSAM AHKY LPAL DEFP HPPK RLRS DPDA CPTM PLLA MLLR GLTQ IQSR ILGP GRKC CALA NLAD MLTV FALT EDDP QEVS ATVY LDKL ATVI SVWN SDTQ NPYH QQAL AEKV KEAE RDVS LTSL AKLP SETI FVGC EFLH HLLR EWGE ELQA VLRS SQGT SYDS YRLC D |
遺伝子ID: | 50628 |
Uniprot: | P57678 |
セルラーロケーション: | Cytoplasm, Nucleus, gem, nucleolus |
計算された分子量: | 120kDa |
観察された分子量: | 120kDa |
同義語: | GEMIN4, HC56, HCAP1, HHRF-1, p97 |
バックグラウンド: | The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. |
UniProt Protein Function: | GEMIN4: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. |
UniProt Protein Details: | Protein type:Nucleolus; RNA splicing; RNA-binding Chromosomal Location of Human Ortholog: 17p13.3 Cellular Component: cytoplasm; cytosol; membrane; nuclear body; nucleoplasm; small nuclear ribonucleoprotein complex; SMN complex Molecular Function:protein binding Biological Process: nuclear import; spliceosomal snRNP biogenesis |
NCBI Summary: | The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | P57678 |
NCBI GenInfo Identifier: | 322510030 |
NCBI Gene ID: | 50628 |
NCBI Accession: | P57678.2 |
UniProt Secondary Accession: | P57678,Q9NZS7, Q9UG32, Q9Y4Q2, |
UniProt Related Accession: | P57678 |
Molecular Weight: | 120kDa |
NCBI Full Name: | Gem-associated protein 4 |
NCBI Synonym Full Names: | gem nuclear organelle associated protein 4 |
NCBI Official Symbol: | GEMIN4 |
NCBI Official Synonym Symbols: | p97; HC56; HCAP1; HHRF-1 |
NCBI Protein Information: | gem-associated protein 4 |
UniProt Protein Name: | Gem-associated protein 4 |
UniProt Synonym Protein Names: | Component of gems 4; p97 |
Protein Family: | Gem-associated protein |
UniProt Gene Name: | GEMIN4 |
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