Anti-GDA Antibody (CAB6441)
- SKU:
- CAB6441
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GDA Antibody |
| 抗体コード: | CAB6441 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-454 of human GDA (NP_004284.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:10 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, SKOV3, mouse liver, mouse brain, rat brain, Mouse lung, Rat testis, NCI-H460 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-454 of human GDA (NP_004284.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FVGK VCMD LNDT FPEY KETT EESI KETE RFVS EMLQ KNYS RVKP IVTP RFSL SCSE TLMG ELGN IAKT RDLH IQSH ISEN RDEV EAVK NLYP SYKN YTSV YDKN NLLT NKTV MAHG CYLS AEEL NVFH ERGA SIAH CPNS NLSL SSGF LNVL EVLK HEVK IGLG TDVA GGYS YSML DAIR RAVM VSNI LLIN KVNE KSLT LKEV FRLA TLGG SQAL GLDG EIGN FEVG KEFD AILI NPKA SDSP IDLF YGDF FGDI SEAV IQKF LYLG DDRN IEEV YVGG KQVV PFSS SV |
| 遺伝子ID: | 9615 |
| Uniprot: | Q9Y2T3 |
| セルラーロケーション: | |
| 計算された分子量: | 42kDa/51kDa/52kDa |
| 観察された分子量: | 51kDa |
| 同義語: | GDA, CYPIN, GUANASE, NEDASIN, GAH |
| バックグラウンド: | This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | GDA: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Belongs to the ATZ/TRZ family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleotide Metabolism - purine; EC 3.5.4.3; Hydrolase Chromosomal Location of Human Ortholog: 9q21.13 Cellular Component: intracellular; cytosol Molecular Function:guanine deaminase activity; zinc ion binding Biological Process: nervous system development; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; purine nucleotide catabolic process; guanine catabolic process; purine base metabolic process |
| NCBI Summary: | This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
| UniProt Code: | Q9Y2T3 |
| NCBI GenInfo Identifier: | 9910736 |
| NCBI Gene ID: | 9615 |
| NCBI Accession: | Q9Y2T3.1 |
| UniProt Secondary Accession: | Q9Y2T3,Q5SZC7, Q9H335, Q9ULG2, B4DTY5, |
| UniProt Related Accession: | Q9Y2T3 |
| Molecular Weight: | 454 |
| NCBI Full Name: | Guanine deaminase |
| NCBI Synonym Full Names: | guanine deaminase |
| NCBI Official Symbol: | GDA |
| NCBI Official Synonym Symbols: | CYPIN; GUANASE; NEDASIN |
| NCBI Protein Information: | guanine deaminase; GAH; p51-nedasin; guanine aminase; guanine aminohydrolase; cytoplasmic PSD95 interactor |
| UniProt Protein Name: | Guanine deaminase |
| UniProt Synonym Protein Names: | Guanine aminohydrolase; GAH; p51-nedasin |
| UniProt Gene Name: | GDA |
| UniProt Entry Name: | GUAD_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GDA Antibody (CAB6441) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunofluorescence analysis of A549 cells using GDA antibody (CAB6441). Blue: DAPI for nuclear staining. |
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