Anti-GDA Antibody (CAB19916)[KO Validated]

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SKU:
CAB19916
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

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抗体名:Anti-GDA Antibody [KO Validated]
抗体コード:CAB19916
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IF
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant protein of human GDA.
申し込み:WB IF
推奨希釈:WB 1:500 - 1:2000 IF 1:10 - 1:100
反応性:Human, Mouse, Rat
ポジティブサンプル:HeLa
免疫原:Recombinant protein of human GDA.
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:9615
Uniprot:Q9Y2T3
セルラーロケーション:
計算された分子量:42kDa/51kDa/52kDa
観察された分子量:45KDa
Anti-GDA Antibody [KO Validated] (CAB19916)Western blot analysis of extracts from normal (control) and GDA knockout (KO) HeLa cells, using GDA antibody (CAB19916) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
同義語:GDA, CYPIN, GUANASE, NEDASIN, GAH
バックグラウンド:This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:GDA: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Belongs to the ATZ/TRZ family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Nucleotide Metabolism - purine; EC 3.5.4.3; Hydrolase

Chromosomal Location of Human Ortholog: 9q21.13

Cellular Component: intracellular; cytosol

Molecular Function:guanine deaminase activity; zinc ion binding

Biological Process: nervous system development; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; purine nucleotide catabolic process; guanine catabolic process; purine base metabolic process

NCBI Summary:This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
UniProt Code:Q9Y2T3
NCBI GenInfo Identifier:9910736
NCBI Gene ID:9615
NCBI Accession:Q9Y2T3.1
UniProt Secondary Accession:Q9Y2T3,Q5SZC7, Q9H335, Q9ULG2, B4DTY5,
UniProt Related Accession:Q9Y2T3
Molecular Weight:454
NCBI Full Name:Guanine deaminase
NCBI Synonym Full Names:guanine deaminase
NCBI Official Symbol:GDA  
NCBI Official Synonym Symbols:CYPIN; GUANASE; NEDASIN  
NCBI Protein Information:guanine deaminase; GAH; p51-nedasin; guanine aminase; guanine aminohydrolase; cytoplasmic PSD95 interactor
UniProt Protein Name:Guanine deaminase
UniProt Synonym Protein Names:Guanine aminohydrolase; GAH; p51-nedasin
UniProt Gene Name:GDA  
UniProt Entry Name:GUAD_HUMAN
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