Anti-GCNT1 Antibody (CAB10842)
- SKU:
- CAB10842
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-GCNT1 Antibody |
抗体コード: | CAB10842 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GCNT1 (NP_001091103.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | A-549, HT-29, SGC-7901 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GCNT1 (NP_001091103.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | FVSV RHLE LAGE NPSS DINC TKVL QGDV NEIQ KVKL EILT VKFK KRPR WTPD DYIN MTSD CSSF IKRR KYIV EPLS KEEA EFPI AYSI VVHH KIEM LDRL LRAI YMPQ NFYC IHVD TKSE DSYL AAVM GIAS CFSN VFVA SRLE SVVY ASWS RVQA DLNC MKDL YAMS ANWK YLIN LCGM DFPI KTNL EIVR KLKL LMGE NNLE TERM PSHK EERW KKRY EVVN GKLT NTGT VKML PPLE TPLF SGSA YFVV SREY VGYV L |
遺伝子ID: | 2650 |
Uniprot: | Q02742 |
セルラーロケーション: | Golgi apparatus membrane, Single-pass type II membrane protein |
計算された分子量: | 49kDa |
観察された分子量: | 50kDa |
同義語: | GCNT1, C2GNT, C2GNT-L, C2GNT1, G6NT, NACGT2, NAGCT2, core 2 |
バックグラウンド: | This gene is a member of the beta-1, 6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
UniProt Protein Function: | GCNT1: Forms critical branches in O-glycans. Belongs to the glycosyltransferase 14 family. |
UniProt Protein Details: | Protein type:EC 2.4.1.102; Transferase; Glycan Metabolism - O-glycan biosynthesis; Membrane protein, integral Chromosomal Location of Human Ortholog: 9q13 Cellular Component: extracellular space; Golgi cisterna; Golgi membrane; integral to membrane; trans-Golgi network Molecular Function:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; protein binding Biological Process: cellular protein metabolic process; glycoprotein biosynthetic process; leukocyte tethering or rolling; O-glycan processing; post-translational protein modification; protein amino acid O-linked glycosylation; response to insulin stimulus; tissue morphogenesis |
NCBI Summary: | This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q02742 |
NCBI GenInfo Identifier: | 218512053 |
NCBI Gene ID: | 2650 |
NCBI Accession: | Q02742.2 |
UniProt Secondary Accession: | Q02742,Q6DJZ4, |
UniProt Related Accession: | Q02742 |
Molecular Weight: | 49,799 Da |
NCBI Full Name: | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
NCBI Synonym Full Names: | glucosaminyl (N-acetyl) transferase 1, core 2 |
NCBI Official Symbol: | GCNT1 |
NCBI Official Synonym Symbols: | G6NT; C2GNT; C2GNT1; NACGT2; NAGCT2; C2GNT-L |
NCBI Protein Information: | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
UniProt Protein Name: | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
UniProt Synonym Protein Names: | Core 2-branching enzyme; Core2-GlcNAc-transferase; C2GNT; Core 2 GNT |
UniProt Gene Name: | GCNT1 |
UniProt Entry Name: | GCNT1_HUMAN |
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