Anti-GCM1 Antibody (CAB7282)
- SKU:
- CAB7282
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-GCM1 Antibody |
抗体コード: | CAB7282 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 207-436 of human GCM1 (NP_003634.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
反応性: | Human |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 207-436 of human GCM1 (NP_003634.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SFQE GVQL PGSY SGHL IANT PQQN SLND CFSF SKSY GLGG ITDL TDQT STVD PMKL YEKR KLSS SRTY SSGD LLPP SASG VYSD HGDL QAWS KNAA LGRN HLAD NCYS NYPF PLTS WPCS FSPS QNSS EPFY QQLP LEPP AAKT GCPP LWPN PAGN LYEE KVHV DFNS YVQS PAYH SPQE DPFL FTYA SHPH QQYS LPSK SSKW DFEE EMTY LGLD HCNN DMLL NLCP LR |
遺伝子ID: | 8521 |
Uniprot: | Q9NP62 |
セルラーロケーション: | Nucleus |
計算された分子量: | 49kDa |
観察された分子量: | Refer to figures |
同義語: | GCM1, GCMA, hGCMa |
バックグラウンド: | This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. |
UniProt Protein Function: | GCM1: Transcription factor that is necessary for placental development. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 6p12.1 Cellular Component: transcription factor complex; nucleus Molecular Function:protein binding; DNA binding; zinc ion binding; histone deacetylase binding; transcription factor binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; positive regulation of syncytium formation by plasma membrane fusion; anatomical structure morphogenesis; regulation of transcription, DNA-dependent; astrocyte fate commitment; positive regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NP62 |
NCBI GenInfo Identifier: | 33516903 |
NCBI Gene ID: | 8521 |
NCBI Accession: | Q9NP62.1 |
UniProt Secondary Accession: | Q9NP62,Q4VAQ7, Q5T0X0, Q99468, Q9P1X3, |
UniProt Related Accession: | Q9NP62 |
Molecular Weight: | 49,268 Da |
NCBI Full Name: | Chorion-specific transcription factor GCMa |
NCBI Synonym Full Names: | glial cells missing homolog 1 (Drosophila) |
NCBI Official Symbol: | GCM1 |
NCBI Official Synonym Symbols: | GCMA; hGCMa |
NCBI Protein Information: | chorion-specific transcription factor GCMa; GCM motif protein 1 |
UniProt Protein Name: | Chorion-specific transcription factor GCMa |
UniProt Synonym Protein Names: | GCM motif protein 1; Glial cells missing homolog 1 |
Protein Family: | Chorion-specific transcription factor |
UniProt Gene Name: | GCM1 |
UniProt Entry Name: | GCM1_HUMAN |
![]() | Immunofluorescence analysis of MCF-7 cells using GCM1 antibody (CAB7282). Blue: DAPI for nuclear staining. |
View AllClose