Anti-GCAT Antibody (CAB15802)
- SKU:
- CAB15802
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-GCAT Antibody |
抗体コード: | CAB15802 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-419 of human GCAT (NP_055106.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse eye |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-419 of human GCAT (NP_055106.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | KAHK YRYR HLDM ADLE AKLQ EAQK HRLR LVAT DGAF SMDG DIAP LQEI CCLA SRYG ALVF MDEC HATG FLGP TGRG TDEL LGVM DQVT IINS TLGK ALGG ASGG YTTG PGPL VSLL RQRA RPYL FSNS LPPA VVGC ASKA LDLL MGSN TIVQ SMAA KTQR FRSK MEAA GFTI SGAS HPIC PVML GDAR LASR MADD MLKR GIFV IGFS YPVV PKGK ARIR VQIS AVHS EEDI DRCV EAFV EVGR LHGA LP |
遺伝子ID: | 23464 |
Uniprot: | O75600 |
セルラーロケーション: | Mitochondrion, Nucleus |
計算された分子量: | 45kDa/47kDa |
観察された分子量: | 45kDa |
同義語: | GCAT, KBL |
バックグラウンド: | The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14. |
UniProt Protein Function: | GCAT: The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14. [provided by RefSeq, Jan 2010] |
UniProt Protein Details: | Protein type:Transferase; Amino Acid Metabolism - glycine, serine and threonine; EC 2.3.1.29; Mitochondrial Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: mitochondrial inner membrane; mitochondrion; nucleoplasm Biological Process: threonine catabolic process to pyruvate |
NCBI Summary: | The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14. [provided by RefSeq, Jan 2010] |
UniProt Code: | O75600 |
NCBI GenInfo Identifier: | 6685545 |
NCBI Gene ID: | 23464 |
NCBI Accession: | O75600.1 |
UniProt Secondary Accession: | O75600,Q6ZWF1, Q96CA9, E2QC23, |
UniProt Related Accession: | O75600 |
Molecular Weight: | 47,974 Da |
NCBI Full Name: | 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial |
NCBI Synonym Full Names: | glycine C-acetyltransferase |
NCBI Official Symbol: | GCAT |
NCBI Official Synonym Symbols: | KBL |
NCBI Protein Information: | 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial |
UniProt Protein Name: | 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial |
UniProt Synonym Protein Names: | Aminoacetone synthase; Glycine acetyltransferase |
UniProt Gene Name: | GCAT |
UniProt Entry Name: | KBL_HUMAN |
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