Anti-GANC Antibody (CAB16377)
- SKU:
- CAB16377
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GANC Antibody |
| 抗体コード: | CAB16377 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GANC (NP_937784.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat kidney |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GANC (NP_937784.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DVLT SKPS TVRL ISCS GDTG SLIL ADGK GDLK CHIT ANPF KVDL VSEE EVVI SINS LGQL YFEH LQIL HKQR AAKE NEEE TSVD TSQE NQED LGLW EEKF G |
| 遺伝子ID: | 2595 |
| Uniprot: | Q8TET4 |
| セルラーロケーション: | |
| 計算された分子量: | 104kDa |
| 観察された分子量: | 104kDa |
| 同義語: | GANC |
| バックグラウンド: | Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1, 4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | GANC: Has alpha-glucosidase activity. Belongs to the glycosyl hydrolase 31 family. |
| UniProt Protein Details: | Protein type:EC 3.2.1.20; Hydrolase; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - galactose Chromosomal Location of Human Ortholog: 15q15.2 |
| NCBI Summary: | Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2014] |
| UniProt Code: | Q8TET4 |
| NCBI GenInfo Identifier: | 296439340 |
| NCBI Gene ID: | 2595 |
| NCBI Accession: | Q8TET4.3 |
| UniProt Secondary Accession: | Q8TET4,Q52LQ4, Q8IWZ0, Q8IZM4, Q8IZM5, |
| UniProt Related Accession: | Q8TET4 |
| Molecular Weight: | 104,334 Da |
| NCBI Full Name: | Neutral alpha-glucosidase C |
| NCBI Synonym Full Names: | glucosidase alpha, neutral C |
| NCBI Official Symbol: | GANC |
| NCBI Protein Information: | neutral alpha-glucosidase C |
| UniProt Protein Name: | Neutral alpha-glucosidase C |
| Protein Family: | Neutral alpha-glucosidase |
| UniProt Gene Name: | GANC |
| UniProt Entry Name: | GANC_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GANC Rabbit pAb (CAB16377) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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