Anti-GALP Antibody (CAB17445)
- SKU:
- CAB17445
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-GALP Antibody |
抗体コード: | CAB17445 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-116 of human GALP (NP_149097.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-116 of human GALP (NP_149097.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | APAH RGRG GWTL NSAG YLLG PVLH LPQM GDQD GKRE TALE ILDL WKAI DGLP YSHP PQPS KRNV METF AKPE IGDL GMLS MKIP KEED VLKS |
遺伝子ID: | 85569 |
Uniprot: | Q9UBC7 |
セルラーロケーション: | |
計算された分子量: | 13kDa |
観察された分子量: | 20kDa |
同義語: | GALP |
バックグラウンド: | This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, has vasoactive properties, displays antimicrobial activity against E. coli, and may serve as a marker for neuroblastic tumors. |
UniProt Protein Function: | GALP: Hypothalamic neuropeptide which binds to the G-protein- coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin- releasing hormone secretion. Isoform 2 exhibits potent and dose- dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2. Belongs to the galanin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 19q13.43 Cellular Component: extracellular region Molecular Function:hormone activity Biological Process: neuropeptide signaling pathway; behavioral response to starvation; defense response to bacterium; regulation of appetite; response to insulin stimulus |
NCBI Summary: | This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, may have vasoactive properties and serve as a marker for neuroblastic tumors.[provided by RefSeq, Mar 2009] |
UniProt Code: | Q9UBC7 |
NCBI GenInfo Identifier: | 20138432 |
NCBI Gene ID: | 85569 |
NCBI Accession: | Q9UBC7.1 |
UniProt Secondary Accession: | Q9UBC7,A1KXL3, |
UniProt Related Accession: | Q9UBC7 |
Molecular Weight: | 5,321 Da |
NCBI Full Name: | Galanin-like peptide |
NCBI Synonym Full Names: | galanin-like peptide |
NCBI Official Symbol: | GALP |
NCBI Protein Information: | galanin-like peptide; alarin; gal-like peptide |
UniProt Protein Name: | Galanin-like peptide |
Protein Family: | Galanin-like peptide |
UniProt Gene Name: | GALP |
UniProt Entry Name: | GALP_HUMAN |
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