Anti-GALNT10 Antibody (CAB14909)
- SKU:
- CAB14909
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GALNT10 Antibody |
| 抗体コード: | CAB14909 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 444-603 of human GALNT10 (NP_938080.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | SGC-7901, OVCAR3, Mouse brain, Mouse testis, Rat heart, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 444-603 of human GALNT10 (NP_938080.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | WDLP KFYP PVEP PAAA WGEI RNVG TGLC ADTK HGAL GSPL RLEG CVRG RGEA AWNN MQVF TFTW REDI RPGD PQHT KKFC FDAI SHTS PVTL YDCH SMKG NQLW KYRK DKTL YHPV SGSC MDCS ESDH RIFM NTCN PSSL TQQW LFEH TNST VLEK FNRN |
| 遺伝子ID: | 55568 |
| Uniprot: | Q86SR1 |
| セルラーロケーション: | Golgi apparatus membrane, Single-pass type II membrane protein |
| 計算された分子量: | 31kDa/41kDa/61kDa/68kDa |
| 観察された分子量: | 69kDa |
| 同義語: | GALNT10, GALNACT10, PPGALNACT10, PPGANTASE10 |
| バックグラウンド: | This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides. |
| UniProt Protein Function: | GALNT10: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Transferase; Glycan Metabolism - O-glycan biosynthesis; EC 2.4.1.41 Chromosomal Location of Human Ortholog: 5q33.2 Cellular Component: Golgi membrane; integral to membrane Molecular Function:metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity; carbohydrate binding Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modification |
| NCBI Summary: | This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides.[provided by RefSeq, Apr 2010] |
| UniProt Code: | Q86SR1 |
| NCBI GenInfo Identifier: | 38195091 |
| NCBI Gene ID: | 55568 |
| NCBI Accession: | NP_938080 |
| UniProt Secondary Accession: | Q86SR1,Q6IN56, Q86VP8, Q8IXJ2, Q8TEJ2, Q96IV2, Q9H8E1 Q9Y4M4, B3KXC9, |
| UniProt Related Accession: | Q86SR1 |
| Molecular Weight: | 31,833 Da |
| NCBI Full Name: | polypeptide N-acetylgalactosaminyltransferase 10 |
| NCBI Synonym Full Names: | polypeptide N-acetylgalactosaminyltransferase 10 |
| NCBI Official Symbol: | GALNT10 |
| NCBI Official Synonym Symbols: | GALNACT10; PPGALNACT10; PPGANTASE10 |
| NCBI Protein Information: | polypeptide N-acetylgalactosaminyltransferase 10; GalNAc transferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) |
| UniProt Protein Name: | Polypeptide N-acetylgalactosaminyltransferase 10 |
| UniProt Synonym Protein Names: | Polypeptide GalNAc transferase 10; GalNAc-T10; pp-GaNTase 10; Protein-UDP acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10 |
| Protein Family: | Polypeptide N-acetylgalactosaminyltransferase |
| UniProt Gene Name: | GALNT10 |
| UniProt Entry Name: | GLT10_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GALNT10 antibody (CAB14909) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
View AllClose