Anti-GABRB2 Antibody (CAB1876)
- SKU:
- CAB1876
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-GABRB2 Antibody |
| 抗体コード: | CAB1876 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-244 of human GABRB2 (NP_000804.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-87MG, HepG2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-244 of human GABRB2 (NP_000804.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SVND PSNM SLVK ETVD RLLK GYDI RLRP DFGG PPVA VGMN IDIA SIDM VSEV NMDY TLTM YFQQ AWRD KRLS YNVI PLNL TLDN RVAD QLWV PDTY FLND KKSF VHGV TVKN RMIR LHPD GTVL YGLR ITTT AACM MDLR RYPL DEQN CTLE IESY GYTT DDIE FYWR GDDN AVTG VTKI ELPQ FSIV DYKL ITKK VVFS TGSY PRLS LSFK LKRN IGY |
| 遺伝子ID: | 2561 |
| Uniprot: | P47870 |
| セルラーロケーション: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse |
| 計算された分子量: | 36kDa/42kDa/54kDa/59kDa |
| 観察された分子量: | 55KDa |
| 同義語: | GABRB2 |
| バックグラウンド: | The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. |
| UniProt Protein Function: | Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel. |
| NCBI Summary: | The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P47870 |
| NCBI GenInfo Identifier: | 292495010 |
| NCBI Gene ID: | 2561 |
| NCBI Accession: | P47870.2 |
| UniProt Related Accession: | P47870 |
| Molecular Weight: | ~ 59kDa |
| NCBI Full Name: | Gamma-aminobutyric acid receptor subunit beta-2 |
| NCBI Synonym Full Names: | gamma-aminobutyric acid type A receptor subunit beta2 |
| NCBI Official Symbol: | GABRB2 |
| NCBI Official Synonym Symbols: | ICEE2 |
| NCBI Protein Information: | gamma-aminobutyric acid receptor subunit beta-2 |
| UniProt Protein Name: | Gamma-aminobutyric acid receptor subunit beta-2 |
| UniProt Synonym Protein Names: | GABA(A) receptor subunit beta-2 |
| UniProt Gene Name: | GABRB2 |
| UniProt Entry Name: | GBRB2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GABRB2 Rabbit pAb (CAB1876) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
View AllClose