Anti-GABPB1 Antibody (CAB6909)
- SKU:
- CAB6909
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-GABPB1 Antibody |
抗体コード: | CAB6909 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 231-395 of human GABPB1 (NP_005245.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
反応性: | Human, Mouse |
ポジティブサンプル: | MCF7, HepG2, BT-474, HT-29, Mouse spleen, Mouse thymus |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 231-395 of human GABPB1 (NP_005245.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | AEAS APLS NSSE TPVV ATEE VVTA ESVD GAIQ QVVS SGGQ QVIT IVTD GIQL GNLH SIPT SGIG QPII VTMP DGQQ VLTV PATD IAEE TVIS EEPP AKRQ CIEI IENR VESA EIEE REAL QKQL DEAN REAQ KYRQ QLLK KEQE AEAY RQKL EAMT RLQT NKEA V |
遺伝子ID: | 2553 |
Uniprot: | Q06547 |
セルラーロケーション: | Nucleus |
計算された分子量: | 36kDa/38kDa/41kDa/42kDa |
観察された分子量: | 50kDa |
同義語: | GABPB1, BABPB2, E4TF1, E4TF1-47, E4TF1-53, E4TF1B, GABPB, GABPB-1, GABPB2, NRF2B1, NRF2B2 |
バックグラウンド: | This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. |
UniProt Protein Function: | GABPB1: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 15q21.2 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; protein heterodimerization activity; transcription factor activity Biological Process: regulation of transcription from RNA polymerase II promoter; mitochondrion organization and biogenesis; transcription, DNA-dependent; organelle organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q06547 |
NCBI GenInfo Identifier: | 23503070 |
NCBI Gene ID: | 2553 |
NCBI Accession: | Q06547.2 |
UniProt Secondary Accession: | Q06547,Q06545, Q12940, Q12941, Q12942, Q8IYD0, A8IE52 |
UniProt Related Accession: | Q06547 |
Molecular Weight: | 395 |
NCBI Full Name: | GA-binding protein subunit beta-1 |
NCBI Synonym Full Names: | GA binding protein transcription factor, beta subunit 1 |
NCBI Official Symbol: | GABPB1 |
NCBI Official Synonym Symbols: | E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; E4TF1-47; E4TF1-53 |
NCBI Protein Information: | GA-binding protein subunit beta-1; GABPB-1; GABP subunit beta-2; nuclear respiratory factor 2; transcription factor E4TF1-47; transcription factor E4TF1-53; GA binding protein transcription factor beta subunit 1 transcript variant gamma-2 |
UniProt Protein Name: | GA-binding protein subunit beta-1 |
UniProt Synonym Protein Names: | GABP subunit beta-2; GABPB-2; Nuclear respiratory factor 2; Transcription factor E4TF1-47; Transcription factor E4TF1-53 |
Protein Family: | GA-binding protein |
UniProt Gene Name: | GABPB1 |
UniProt Entry Name: | GABP1_HUMAN |
View AllClose