Anti-FOXK2 Antibody (CAB14245)
- SKU:
- CAB14245
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-FOXK2 Antibody |
抗体コード: | CAB14245 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 511-660 of human FOXK2 (NP_004505.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse kidney, Rat lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 511-660 of human FOXK2 (NP_004505.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | PKAE AQEN GDHR EVKV KVEP IPAI GHAT LGTA SRII QTAQ TTPV QTVT IVQQ APLG QHQL PIKT VTQN GTHV ASVP TAVH GQVN NAAA SPLH MLAT HASA SASL PTKR HNGD QPEQ PELK RIKT EDGE GIVI ALSV DTPP AAVR EKGV QN |
遺伝子ID: | 3607 |
Uniprot: | Q01167 |
セルラーロケーション: | Nucleus |
計算された分子量: | 34kDa/64kDa/69kDa |
観察された分子量: | 69kDa |
同義語: | FOXK2, ILF, ILF-1, ILF1 |
バックグラウンド: | The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. |
UniProt Protein Function: | Transcriptional regulator that recognizes the core sequence 5'-TAAACA-3'. Binds to NFAT-like motifs (purine-rich) in the IL2 promoter (PubMed:1339390). Positively regulates WNT/beta-catenin signaling by translocating DVL proteins into the nucleus (PubMed:25805136). Also binds to HIV-1 long terminal repeat. May be involved in both positive and negative regulation of important viral and cellular promoter elements (PubMed:1909027). |
NCBI Summary: | The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q01167 |
NCBI GenInfo Identifier: | 118572648 |
NCBI Gene ID: | 3607 |
NCBI Accession: | Q01167.3 |
UniProt Secondary Accession: | Q01167,Q13622, Q13623, Q13624, A6NEP5, |
UniProt Related Accession: | Q01167 |
Molecular Weight: | 34,325 Da |
NCBI Full Name: | Forkhead box protein K2 |
NCBI Synonym Full Names: | forkhead box K2 |
NCBI Official Symbol: | FOXK2 |
NCBI Official Synonym Symbols: | ILF; ILF1; ILF-1 |
NCBI Protein Information: | forkhead box protein K2 |
UniProt Protein Name: | Forkhead box protein K2 |
UniProt Synonym Protein Names: | Cellular transcription factor ILF-1; FOXK1; Interleukin enhancer-binding factor 1 |
Protein Family: | Forkhead box protein |
UniProt Gene Name: | FOXK2 |
UniProt Entry Name: | FOXK2_HUMAN |
View AllClose