Anti-FNTB Antibody (CAB15671)
- SKU:
- CAB15671
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-FNTB Antibody |
| 抗体コード: | CAB15671 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human FNTB (NP_002019.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, HeLa, HepG2, K-562, Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human FNTB (NP_002019.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MASP SSFT YYCP PSSS PVWS EPLY SLRP EHAR ERLQ DDSV ETVT SIEQ AKVE EKIQ EVFS SYKF NHLV PRLV LQRE KHFH YLKR GLRQ LTDA YECL DASR PWLC YWIL HSLE LLDE PIPQ |
| 遺伝子ID: | 2342 |
| Uniprot: | P49356 |
| セルラーロケーション: | |
| 計算された分子量: | 43kDa/48kDa |
| 観察された分子量: | 49kDa |
| 同義語: | FNTB, FPTB, farnesyltransferase, CAAX box, beta |
| バックグラウンド: |
| UniProt Protein Function: | FNTB: a subunit of farnesyltransferase that is responsible for peptide-binding. Farnesyltransferase catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. |
| UniProt Protein Details: | Protein type:Transferase; EC 2.5.1.58 Chromosomal Location of Human Ortholog: 14q23.3 Cellular Component: cytosol; microtubule associated complex Molecular Function:protein binding; protein farnesyltransferase activity; zinc ion binding Biological Process: protein farnesylation; regulation of rhodopsin mediated signaling |
| NCBI Summary: | This locus represents naturally occurring read-through transcription between the neighboring CHURC1 (churchill domain containing 1) and FNTB (farnesyltransferase, CAAX box, beta) on chromosome 14. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Feb 2011] |
| UniProt Code: | P49356 |
| NCBI GenInfo Identifier: | 1346696 |
| NCBI Gene ID: | 100529261 |
| NCBI Accession: | P49356.1 |
| UniProt Secondary Accession: | P49356,B2RDX6, B4E1A0, |
| Molecular Weight: | 43,574 Da |
| NCBI Full Name: | Protein farnesyltransferase subunit beta |
| NCBI Synonym Full Names: | CHURC1-FNTB readthrough |
| NCBI Official Symbol: | CHURC1-FNTB |
| NCBI Protein Information: | CHURC1-FNTB protein |
| UniProt Protein Name: | Protein farnesyltransferase subunit beta |
| UniProt Synonym Protein Names: | CAAX farnesyltransferase subunit beta; Ras proteins prenyltransferase subunit beta |
| UniProt Gene Name: | FNTB |
| UniProt Entry Name: | FNTB_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FNTB antibody (CAB15671) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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