Anti-FN3K Antibody (CAB13727)
- SKU:
- CAB13727
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-FN3K Antibody |
| 抗体コード: | CAB13727 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FN3K (NP_071441.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HeLa, Mouse brain, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FN3K (NP_071441.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEQL LRAE LRTA TLRA FGGP GAGC ISEG RAYD TDAG PVFV KVNR RTQA RQMF EGEV ASLE ALRS TGLV RVPR PMKV IDLP GGGA AFVM EHLK MKSL SSQA SKLG EQMA DLHL YNQK LREK LKEE ENTV GRRG EGAE PQYV DKFG FHTV TCCG FIPQ VNEW QDDW PTFF ARHR LQAQ LDLI EKDY ADRE AREL WSRL QVKI |
| 遺伝子ID: | 64122 |
| Uniprot: | Q9H479 |
| セルラーロケーション: | |
| 計算された分子量: | 35kDa |
| 観察された分子量: | 35kDa |
| 同義語: | FN3K |
| バックグラウンド: | A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. |
| UniProt Protein Function: | FN3K: May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme. Belongs to the fructosamine kinase family. |
| UniProt Protein Details: | Protein type:EC 2.7.1.-; Kinase, other Chromosomal Location of Human Ortholog: 17q25.3 Molecular Function:fructosamine-3-kinase activity Biological Process: fructoselysine metabolic process; epithelial cell differentiation; fructosamine metabolic process; phosphorylation |
| NCBI Summary: | A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012] |
| UniProt Code: | Q9H479 |
| NCBI GenInfo Identifier: | 11545906 |
| NCBI Gene ID: | 64122 |
| NCBI Accession: | NP_071441.1 |
| UniProt Related Accession: | Q9H479 |
| Molecular Weight: | |
| NCBI Full Name: | fructosamine-3-kinase |
| NCBI Synonym Full Names: | fructosamine 3 kinase |
| NCBI Official Symbol: | FN3K |
| NCBI Protein Information: | fructosamine-3-kinase |
| UniProt Protein Name: | Fructosamine-3-kinase |
| Protein Family: | Fructosamine-3-kinase |
| UniProt Gene Name: | FN3K |
| UniProt Entry Name: | FN3K_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FN3K antibody (CAB13727) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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