Anti-FMNL1 Antibody (CAB13010)
- SKU:
- CAB13010
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-FMNL1 Antibody |
| 抗体コード: | CAB13010 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 900-1070 of human FMNL1 (NP_005883.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | LO2, A-549, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 900-1070 of human FMNL1 (NP_005883.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DLHF LDKA GSVS LDSV LADV RSLQ RGLE LTQR EFVR QDDC MVLK EFLR ANSP TMDK LLAD SKTA QEAF ESVV EYFG ENPK TTSP GLFF SLFS RFIK AYKK AEQE VEQW KKEA AAQE AGAD TPGK GEPP APKS PPKA RRPQ MDLI SELK RRQQ KEPL IYES DRDG AIED IIT |
| 遺伝子ID: | 752 |
| Uniprot: | O95466 |
| セルラーロケーション: | Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Lipid-anchor, bleb, cell cortex, phagosome |
| 計算された分子量: | 121kDa/122kDa/128kDa |
| 観察された分子量: | 150kDa |
| 同義語: | FMNL1, C17orf1, C17orf1B, FHOD4, FMNL, KW-13 |
| バックグラウンド: | This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. |
| UniProt Protein Function: | FMNL1: May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. Belongs to the formin homology family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q21 Cellular Component: membrane; plasma membrane; phagocytic vesicle; cell cortex; cytosol Molecular Function:actin filament binding; protein binding; Rac GTPase binding; GTPase activating protein binding; profilin binding Biological Process: substrate-bound cell migration; regulation of cell shape; actin filament severing; cortical actin cytoskeleton organization and biogenesis |
| UniProt Code: | O95466 |
| NCBI GenInfo Identifier: | 1519314519 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_005883 |
| Molecular Weight: | 122kDa |
| NCBI Full Name: | formin-like protein 1 |
| UniProt Protein Name: | Formin-like protein 1 |
| UniProt Synonym Protein Names: | CLL-associated antigen KW-13; Leukocyte formin |
| UniProt Gene Name: | FMNL1 |
| UniProt Entry Name: | FMNL_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FMNL1 antibody (CAB13010) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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