Anti-FKBP2 Antibody (CAB8120)
- SKU:
- CAB8120
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | FKBP2 Rabbit Polyclonal Antibody |
抗体コード: | CAB8120 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-142 of human FKBP2 (NP_004461.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | MCF7, SKOV3, Jurkat, HeLa, Mouse thymus, Mouse liver, Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-142 of human FKBP2 (NP_004461.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ATGA EGKR KLQI GVKK RVDH CPIK SRKG DVLH MHYT GKLE DGTE FDSS LPQN QPFV FSLG TGQV IKGW DQGL LGMC EGEK RKLV IPSE LGYG ERGA PPKI PGGA TLVF EVEL LKIE RRTE L |
遺伝子ID: | 2286 |
Uniprot: | P26885 |
セルラーロケーション: | Endoplasmic reticulum membrane, Peripheral membrane protein |
計算された分子量: | 15kDa |
観察された分子量: | 14kDa |
同義語: | FKBP2, FKBP-13, PPIase |
バックグラウンド: | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
UniProt Protein Function: | FKBP2: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the FKBP-type PPIase family. FKBP2 subfamily. |
UniProt Protein Details: | Protein type:EC 5.2.1.8; Endoplasmic reticulum; Isomerase Chromosomal Location of Human Ortholog: 11q13.1 Cellular Component: endoplasmic reticulum Molecular Function:FK506 binding; peptidyl-prolyl cis-trans isomerase activity; protein binding |
NCBI Summary: | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008] |
UniProt Code: | P26885 |
NCBI GenInfo Identifier: | 23503054 |
NCBI Gene ID: | 2286 |
NCBI Accession: | P26885.2 |
UniProt Secondary Accession: | P26885,Q5BJH9, Q9BTS7, |
UniProt Related Accession: | P26885 |
Molecular Weight: | 16kDa |
NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase FKBP2 |
NCBI Synonym Full Names: | FK506 binding protein 2 |
NCBI Official Symbol: | FKBP2 |
NCBI Official Synonym Symbols: | PPIase; FKBP-13 |
NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase FKBP2 |
UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase FKBP2 |
UniProt Synonym Protein Names: | 13 kDa FK506-binding protein; 13 kDa FKBP; FKBP-13; FK506-binding protein 2; FKBP-2; Immunophilin FKBP13; Rotamase |
Protein Family: | FK506-binding protein |
UniProt Gene Name: | FKBP2 |
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