Anti-FGGY Antibody (CAB14904)
- SKU:
- CAB14904
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-FGGY Antibody |
| 抗体コード: | CAB14904 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human FGGY (NP_060761.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, HepG2, A-431, Mouse kidney, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human FGGY (NP_060761.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSGG EQKP ERYY VGVD VGTG SVRA ALVD QSGV LLAF ADQP IKNW EPQF NHHE QSSE DIWA ACCV VTKK VVQG IDLN QIRG LGFD ATCS LVVL DKQF HPLP VNQE GDSH RNVI MWLD HRAV SQVN RINE TKHS VLQY VGGV MSVE MQAP KLLW LKEN LREI CWDK AGHF FDLP DFLS WKAT GVTA RSLC SLVC KWTY SAEK GWDD SFWK MIGL EDFV ADNY SKIG NQVL PPGA SLGN GLTP EAAR DLGL LP |
| 遺伝子ID: | 55277 |
| Uniprot: | Q96C11 |
| セルラーロケーション: | |
| 計算された分子量: | 26kDa/27kDa/47kDa/50kDa/59kDa/62kDa |
| 観察された分子量: | 70kDa |
| 同義語: | FGGY |
| バックグラウンド: | This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | FGGY: Defects in FGGY are associated with sporadic amyotrophic lateral sclerosis (ALS). Amyotrophic lateral sclerosis is a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. Belongs to the FGGY kinase family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Kinase, other; EC 2.7.1.- Chromosomal Location of Human Ortholog: 1p32.1 Molecular Function:kinase activity; phosphotransferase activity, alcohol group as acceptor Biological Process: carbohydrate metabolic process; phosphorylation |
| UniProt Code: | Q96C11 |
| NCBI GenInfo Identifier: | 164663828 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_060761 |
| Molecular Weight: | |
| NCBI Full Name: | FGGY carbohydrate kinase domain-containing protein isoform b |
| UniProt Protein Name: | FGGY carbohydrate kinase domain-containing protein |
| Protein Family: | FGGY carbohydrate kinase domain-containing protein |
| UniProt Gene Name: | FGGY |
| UniProt Entry Name: | FGGY_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FGGY antibody (CAB14904) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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