Anti-FGF7/KGF Antibody (CAB5966)
- SKU:
- CAB5966
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HBGF-7
- Synonyms:
- KGF
Description
| 抗体名: | FGF7/KGF Rabbit mAb |
| 抗体コード: | CAB5966 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | HBGF-7, KGF |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human FGF7/FGF7/KGF |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, A-549, Raji, Mouse lung, Mouse spleen, Mouse uterus, Rat lung, Rat spleen, Rat uterus |
| 免疫原: | A synthesized peptide derived from human FGF7/FGF7/KGF |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 2252 |
| Uniprot: | P21781 |
| 計算された分子量: | 28kDa |
| 観察された分子量: | 23KDa |
| UniProt Protein Function: | FGF7: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. Belongs to the heparin-binding growth factors family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Cytokine Chromosomal Location of Human Ortholog: 15q21.2 Cellular Component: Golgi apparatus; extracellular region Molecular Function:heparin binding; protein binding; growth factor activity; fibroblast growth factor receptor binding; chemoattractant activity Biological Process: epidermal growth factor receptor signaling pathway; positive regulation of keratinocyte migration; epidermis development; fibroblast growth factor receptor signaling pathway; hair follicle morphogenesis; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; mesenchymal cell proliferation; signal transduction; positive regulation of peptidyl-tyrosine phosphorylation; positive chemotaxis; positive regulation of cell division; positive regulation of cell proliferation; actin cytoskeleton reorganization; insulin receptor signaling pathway; response to wounding; innate immune response; positive regulation of epithelial cell proliferation |
| NCBI Summary: | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P21781 |
| NCBI GenInfo Identifier: | 122756 |
| NCBI Gene ID: | 2252 |
| NCBI Accession: | P21781.1 |
| UniProt Secondary Accession: | P21781,Q6FGV5, Q96FG5, H0YNY5, |
| UniProt Related Accession: | P21781 |
| Molecular Weight: | 11,520 Da |
| NCBI Full Name: | Fibroblast growth factor 7 |
| NCBI Synonym Full Names: | fibroblast growth factor 7 |
| NCBI Official Symbol: | FGF7 |
| NCBI Official Synonym Symbols: | KGF; HBGF-7 |
| NCBI Protein Information: | fibroblast growth factor 7; FGF-7; keratinocyte growth factor; heparin-binding growth factor 7 |
| UniProt Protein Name: | Fibroblast growth factor 7 |
| UniProt Synonym Protein Names: | Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor |
| UniProt Gene Name: | FGF7 |
| UniProt Entry Name: | FGF7_HUMAN |