| UniProt Protein Function: | FCGR1B: May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response. Belongs to the immunoglobulin superfamily. FCGR1 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Receptor, misc.; Immunoglobulin superfamily; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p11.2 Cellular Component: early endosome membrane; plasma membrane Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; receptor-mediated endocytosis |
| NCBI Summary: | Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene encodes the low affinity FcgammaRIB receptor that may play an important role in humoral immune response. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q92637 |
| NCBI GenInfo Identifier: | 74760649 |
| NCBI Gene ID: | 2210 |
| NCBI Accession: | Q92637.1 |
| UniProt Secondary Accession: | Q92637,Q7KZ13, Q92638, |
| UniProt Related Accession: | Q92637 |
| Molecular Weight: | 22,136 Da |
| NCBI Full Name: | High affinity immunoglobulin gamma Fc receptor IB |
| NCBI Synonym Full Names: | Fc fragment of IgG receptor Ib |
| NCBI Official Symbol: | FCGR1B |
| NCBI Official Synonym Symbols: | CD64b; IGFRB |
| NCBI Protein Information: | high affinity immunoglobulin gamma Fc receptor IB |
| UniProt Protein Name: | High affinity immunoglobulin gamma Fc receptor IB |
| UniProt Synonym Protein Names: | Fc-gamma RIB; FcRIB; hFcgammaRIB |
| Protein Family: | High affinity immunoglobulin gamma Fc receptor |
| UniProt Gene Name: | FCGR1B |
| UniProt Entry Name: | FCGRB_HUMAN |
