Anti-FBXL14 Antibody (CAB17832)
- SKU:
- CAB17832
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-FBXL14 Antibody |
| 抗体コード: | CAB17832 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-418 of human FBXL14 (NP_689654.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-431, HepG2, Mouse thymus, Mouse spleen, Mouse brain, Rat thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-418 of human FBXL14 (NP_689654.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | METH ISCL FPEL LAMI FGYL DVRD KGRA AQVC TAWR DAAY HKSV WRGV EAKL HLRR ANPS LFPS LQAR GIRR VQIL SLRR SLSY VIQG MANI ESLN LSGC YNLT DNGL GHAF VQEI GSLR ALNL SLCK QITD SSLG RIAQ YLKG LEVL ELGG CSNI TNTG LLLI AWGL QRLK SLNL RSCR HLSD VGIG HLAG MTRS AAEG CLGL EQLT LQDC QKLT DLSL KHIS RGLT GLRL LNLS FCGG ISDA GLLH LSHM GSLR SLNL RSCD NISD TGIM HLAM GSLR LSGL DVSF CDKV GDQS LAYI AQGL DGLK SLSL CSCH ISDD GINR MVRQ MHGL RTLN IGQC VRIT DKGL ELIA EHLS QLTG IDLY GCTR ITKR GLER ITQL PCLK VLNL GLWQ MTDS EKEA RGDF SPLF TVRT RGSS RR |
| 遺伝子ID: | 144699 |
| Uniprot: | Q8N1E6 |
| セルラーロケーション: | |
| 計算された分子量: | 45kDa |
| 観察された分子量: | 46kDa |
 | Western blot - FBXL14 Polyclonal Antibody (CAB17832) |
| 同義語: | Fbl14, FBXL14 |
| バックグラウンド: | Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
| UniProt Protein Function: | FBXL14: Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 12p13.33 Cellular Component: cytoplasm; Golgi apparatus; nucleoplasm Molecular Function:protein binding; ubiquitin-protein ligase activity Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process |
| NCBI Summary: | Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8N1E6 |
| NCBI GenInfo Identifier: | 48428083 |
| NCBI Gene ID: | 144699 |
| NCBI Accession: | Q8N1E6.1 |
| UniProt Related Accession: | Q8N1E6 |
| Molecular Weight: | 45,886 Da |
| NCBI Full Name: | F-box/LRR-repeat protein 14 |
| NCBI Synonym Full Names: | F-box and leucine rich repeat protein 14 |
| NCBI Official Symbol: | FBXL14 |
| NCBI Official Synonym Symbols: | Fbl14 |
| NCBI Protein Information: | F-box/LRR-repeat protein 14 |
| UniProt Protein Name: | F-box/LRR-repeat protein 14 |
| UniProt Synonym Protein Names: | F-box and leucine-rich repeat protein 14 |
| UniProt Gene Name: | FBXL14 |
| UniProt Entry Name: | FXL14_HUMAN |