Anti-FAM65B Antibody (CAB9234)
- SKU:
- CAB9234
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-FAM65B Antibody |
| 抗体コード: | CAB9234 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human FAM65B (NP_056948.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, Mouse thymus, Mouse brain, Rat thymus, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human FAM65B (NP_056948.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MLVG SQSF SPGG PNGI IRSQ SFAG FSGL QERR SRCN SFIE NSSA LKKP QAKL KKMH NLGH KNNN PPKE PQPK RVEE VYRA LKNG LDEY LEVH QTEL DKLT AQLK DMKR NSRL GVLY DLDK QIKT IERY MRRL EFHI SKVD ELYE AYCI QRRL QDGA SKMK QAFA TSPA SKAA RESL TEIN RSFK EYTE NMCT IEVE LENL LGEF SIKM KG |
| 遺伝子ID: | 9750 |
| Uniprot: | Q9Y4F9 |
| セルラーロケーション: | Cell projection, Cytoplasm, Mitochondrion, cytoskeleton, filopodium, stereocilium membrane |
| 計算された分子量: | 65kDa/118kDa |
| 観察された分子量: | 118kDa |
| 同義語: | RIPOR2, C6orf32, DFNB104, DIFF40, DIFF48, FAM65B, MYONAP, PL48 |
| バックグラウンド: | This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients. |
| UniProt Protein Function: | FAM65B: Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation. Belongs to the FAM65 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 6p22.3-p21.32 Cellular Component: cytoplasm Molecular Function:protein binding Biological Process: sensory perception of sound Disease: Deafness, Autosomal Recessive 104 |
| NCBI Summary: | The protein encoded by this gene stimulates the formation of a non-mitotic multinucleate syncytium from proliferative cytotrophoblasts during trophoblast differentiation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2013] |
| UniProt Code: | Q9Y4F9 |
| NCBI GenInfo Identifier: | 296439477 |
| NCBI Gene ID: | 9750 |
| NCBI Accession: | Q9Y4F9.4 |
| UniProt Secondary Accession: | Q9Y4F9,Q13529, Q5VV37, Q5VV38, Q9BQ28, A6NHP2, |
| UniProt Related Accession: | Q9Y4F9 |
| Molecular Weight: | 65,692 Da |
| NCBI Full Name: | Protein FAM65B |
| NCBI Synonym Full Names: | family with sequence similarity 65 member B |
| NCBI Official Symbol: | FAM65B |
| NCBI Official Synonym Symbols: | PL48; DIFF40; DIFF48; MYONAP; C6orf32; DFNB104 |
| NCBI Protein Information: | protein FAM65B |
| UniProt Protein Name: | Protein FAM65B |
| Protein Family: | Protein |
| UniProt Gene Name: | FAM65B |
| UniProt Entry Name: | FA65B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FAM65B antibody (CAB9234) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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