| UniProt Protein Function: | FAM120A: May participate in mRNA transport in the cytoplasm. Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous- type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. Belongs to the constitutive coactivator of PPAR-gamma family. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding; Tumor suppressor Chromosomal Location of Human Ortholog: 9q22.31 Cellular Component: membrane; cytoplasm; plasma membrane |
| UniProt Code: | Q9NZB2 |
| NCBI GenInfo Identifier: | 158523294 |
| NCBI Gene ID: | |
| NCBI Accession: | Q9NZB2.2 |
| Molecular Weight: | 122; 69; 117; 72; 125; 122kDa |
| NCBI Full Name: | Constitutive coactivator of PPAR-gamma-like protein 1 |
| UniProt Protein Name: | Constitutive coactivator of PPAR-gamma-like protein 1 |
| UniProt Synonym Protein Names: | Oxidative stress-associated Src activator; Protein FAM120A |
| Protein Family: | Constitutive coactivator of PPAR-gamma-like protein |
| UniProt Gene Name: | FAM120A |
| UniProt Entry Name: | F120A_HUMAN |
