Anti-EXOG Antibody (CAB3364)
- SKU:
- CAB3364
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-EXOG Antibody |
| 抗体コード: | CAB3364 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 144-368 of human EXOG (NP_005098.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | HeLa, SW620, MCF7, Jurkat |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 144-368 of human EXOG (NP_005098.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AGNN KFSS KAMA ETFY LSNI VPQD FDNN SGYW NRIE MYCR ELTE RFED VWVV SGPL TLPQ TRGD GKKI VSYQ VIGE DNVA VPSH LYKV ILAR RSSV STEP LALG AFVV PNEA IGFQ PQLT EFQV SLQD LEKL SGLV FFPH LDRT SDIR NICS VDTC KLLD FQEF TLYL STRK IEGA RSVL RLEK IMEN LKNA EIEP DDYF MSRY EKKL EELK AKEQ SGTQ IRKP S |
| 遺伝子ID: | 9941 |
| Uniprot: | Q9Y2C4 |
| セルラーロケーション: | Mitochondrion inner membrane |
| 計算された分子量: | 16kDa/26kDa/35kDa/41kDa |
| 観察された分子量: | 41kDa |
| 同義語: | EXOG, ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGL-b, ENGLA, ENGLB |
| バックグラウンド: | This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. |
| UniProt Protein Function: | ENDOGL1: Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single stranded DNA and 5'-3' exonuclease activity. Belongs to the DNA/RNA non-specific endonuclease family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Mitochondrial; Deoxyribonuclease; Ribonuclease; EC 3.1.30.- Chromosomal Location of Human Ortholog: 3p21.3 Cellular Component: mitochondrion; mitochondrial inner membrane Molecular Function:nucleic acid binding; metal ion binding; endonuclease activity Biological Process: DNA catabolic process, endonucleolytic |
| NCBI Summary: | This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009] |
| UniProt Code: | Q9Y2C4 |
| NCBI GenInfo Identifier: | 193806336 |
| NCBI Gene ID: | 9941 |
| NCBI Accession: | Q9Y2C4.2 |
| UniProt Secondary Accession: | Q9Y2C4,Q3SXM9, Q9Y2C8, A8K242, B4DVG2, |
| UniProt Related Accession: | Q9Y2C4 |
| Molecular Weight: | 368 |
| NCBI Full Name: | Nuclease EXOG, mitochondrial |
| NCBI Synonym Full Names: | endo/exonuclease (5'-3'), endonuclease G-like |
| NCBI Official Symbol: | EXOG |
| NCBI Official Synonym Symbols: | ENGL; ENGLA; ENGLB; ENGL-a; ENGL-b; ENDOGL1; ENDOGL2 |
| NCBI Protein Information: | nuclease EXOG, mitochondrial; endo G-like 1; endonuclease G-like 1; endonuclease G-like 2 |
| UniProt Protein Name: | Nuclease EXOG, mitochondrial |
| UniProt Synonym Protein Names: | Endonuclease G-like 1; Endo G-like 1 |
| Protein Family: | Exoglucanase |
| UniProt Gene Name: | EXOG |
| UniProt Entry Name: | EXOG_HUMAN |
 | Western blot analysis of extracts of various cell lines, using EXOG antibody (CAB3364) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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