Anti-ETS2 Antibody (CAB14486)
- SKU:
- CAB14486
- Product type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-ETS2 Antibody |
抗体コード: | CAB14486 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-345 of human ETS2 (NP_005230.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-345 of human ETS2 (NP_005230.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | QMIK ENQE KTED QYEE NSHL TSVP HWIN SNTL GFGT EQAP YGMQ TQNY PKGG LLDS MCPA STPS VLSS EQEF QMFP KSRL SSVS VTYC SVSQ DFPG SNLN LLTN NSGT PKDH DSPE NGAD SFES SDSL LQSW NSQS SLLD VQRV PSFE SFED DCSQ SLCL NKPT MSFK DYIQ ERSD PVEQ G |
遺伝子ID: | 2114 |
Uniprot: | P15036 |
セルラーロケーション: | Nucleus |
計算された分子量: | 53kDa |
観察された分子量: | Refer to Figures |
同義語: | ETS2, ETS2IT1 |
バックグラウンド: | This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Ets-2: a proto-oncogenic transcription factor homologous to the v-ets erythroblastosis virus E26 oncogene. A target of the Akt/JNK signaling pathway in macrophages. A PKC pathway activates ETS2, up-regulating GM-CSF in non-small lung carcinoma cells. |
UniProt Protein Details: | Protein type:Transcription factor; Oncoprotein; DNA-binding Chromosomal Location of Human Ortholog: 21q22.2 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; DNA binding; transcription factor activity; glucocorticoid receptor binding Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; cell differentiation; skeletal development |
NCBI Summary: | This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
UniProt Code: | P15036 |
NCBI GenInfo Identifier: | 119645 |
NCBI Gene ID: | 2114 |
NCBI Accession: | P15036.1 |
UniProt Secondary Accession: | P15036,A1A4L6, |
UniProt Related Accession: | P15036 |
Molecular Weight: | 469 |
NCBI Full Name: | Protein C-ets-2 |
NCBI Synonym Full Names: | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
NCBI Official Symbol: | ETS2 |
NCBI Official Synonym Symbols: | ETS2IT1 |
NCBI Protein Information: | protein C-ets-2; oncogene ETS-2; v-ets erythroblastosis virus E26 oncogene homolog 2; v-ets avian erythroblastosis virus E2 oncogene homolog 2 |
UniProt Protein Name: | Protein C-ets-2 |
Protein Family: | Protein |
UniProt Gene Name: | ETS2 |
UniProt Entry Name: | ETS2_HUMAN |
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