Anti-ERP29 Antibody (CAB7959)[KO Validated]
![Anti-ERP29 Antibody (CAB7959)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/608x608/products/25586/25434/anti-erp29-antibody-cab7959ko-validated__27838__10082.1645806298.jpg?c=1 "Anti-ERP29 Antibody (CAB7959)[KO Validated]")
- SKU:
- CAB7959
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
![Anti-ERP29 Antibody (CAB7959)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/1280x1280/products/25586/25434/anti-erp29-antibody-cab7959ko-validated__27838__10082.1645806298.jpg?c=1&imbypass=on "Anti-ERP29 Antibody (CAB7959)[KO Validated]")
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Description
| 抗体名: | [KO Validated] ERP29 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB7959 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of human ERP29 |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HL-60, THP-1, HeLa, 293T, Mouse testis, Mouse pancreas, Mouse thymus, Mouse spleen |
| 免疫原: | A synthetic peptide of human ERP29 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 10961 |
| Uniprot: | P30040 |
| セルラーロケーション: | Endoplasmic reticulum lumen, Melanosome |
| 計算された分子量: | 5kDa/28kDa |
| 観察された分子量: | 29kDa |
| 同義語: | ERP29, C12orf8, ERp28, ERp31, HEL-S-107, PDI-DB, PDIA9 |
| バックグラウンド: | This gene encodes a protein which localizes to the lumen of the endoplasmic reticulum (ER). It is a member of the protein disulfide isomerase (PDI) protein family but lacks an active thioredoxin motif, suggesting that this protein does not function as a disulfide isomerase. The canonical protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | ERP29: Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER. |
| UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 12q24.13 Cellular Component: cell surface; endoplasmic reticulum; membrane; smooth endoplasmic reticulum; transport vesicle Molecular Function:chaperone binding; protein disulfide isomerase activity; protein homodimerization activity Biological Process: activation of MAPK activity; intracellular protein transport; negative regulation of protein secretion; positive regulation of protein amino acid phosphorylation |
| NCBI Summary: | This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P30040 |
| NCBI GenInfo Identifier: | 6015110 |
| NCBI Gene ID: | 10961 |
| NCBI Accession: | P30040.4 |
| UniProt Secondary Accession: | P30040,Q3MJC3, Q6FHT4, C9J183, |
| UniProt Related Accession: | P30040 |
| Molecular Weight: | 5,477 Da |
| NCBI Full Name: | Endoplasmic reticulum resident protein 29 |
| NCBI Synonym Full Names: | endoplasmic reticulum protein 29 |
| NCBI Official Symbol: | ERP29 |
| NCBI Official Synonym Symbols: | ERp28; ERp31; PDIA9; PDI-DB; C12orf8; HEL-S-107 |
| NCBI Protein Information: | endoplasmic reticulum resident protein 29 |
| UniProt Protein Name: | Endoplasmic reticulum resident protein 29 |
| UniProt Synonym Protein Names: | Endoplasmic reticulum resident protein 28; ERp28; Endoplasmic reticulum resident protein 31; ERp31 |
| Protein Family: | Endoplasmic reticulum resident protein |
| UniProt Gene Name: | ERP29 |
| UniProt Entry Name: | ERP29_HUMAN |
![Anti-ERP29 Polyclonal Antibody [KO Validated] (CAB7959)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/s/034/A7959_1__03794.jpg) | Western blot analysis of extracts of various cell lines, using ERP29 antibody (CAB7959) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
![Anti-ERP29 Polyclonal Antibody [KO Validated] (CAB7959)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/m/259/A7959_2__06748.jpg) | Western blot analysis of extracts from normal (control) and ERP29 knockout (KO) 293T cells, using ERP29 antibody (CAB7959) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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