Anti-ERCC4 Antibody (CAB8119)
- SKU:
- CAB8119
- Product type:
- Antibody
- Application:
- WB
- Application:
- IP
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | ERCC4 Rabbit Polyclonal Antibody |
抗体コード: | CAB8119 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IP |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human ERCC4 (NP_005227.1). |
申し込み: | WB IP |
推奨希釈: | WB 1:500 - 1:2000 IP 1:20 - 1:50 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-251MG, HT-1080 |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human ERCC4 (NP_005227.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | GKPL RVYF LIYG GSTE EQRY LTAL RKEK EAFE KLIR EKAS MVVP EERE GRDE TNLD LVRG TASA DVST DTRK AGGQ EQNG TQQS IVVD MREF RSEL PSLI H |
遺伝子ID: | 2072 |
Uniprot: | Q92889 |
セルラーロケーション: | Nucleus |
計算された分子量: | 42kDa/104kDa |
観察された分子量: | 120kDa |
同義語: | ERCC4, ERCC11, FANCQ, RAD1, XFEPS, XPF |
バックグラウンド: | The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). |
UniProt Protein Function: | Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link. |
NCBI Summary: | The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009] |
UniProt Code: | Q92889 |
NCBI GenInfo Identifier: | 4885217 |
NCBI Gene ID: | 2072 |
NCBI Accession: | NP_005227.1 |
UniProt Secondary Accession: | Q92889,O00140, Q8TD83, A5PKV6, A8K111, |
UniProt Related Accession: | Q92889 |
Molecular Weight: | 103 kDa |
NCBI Full Name: | DNA repair endonuclease XPF |
NCBI Synonym Full Names: | ERCC excision repair 4, endonuclease catalytic subunit |
NCBI Official Symbol: | ERCC4 |
NCBI Official Synonym Symbols: | XPF; RAD1; FANCQ; XFEPS; ERCC11 |
NCBI Protein Information: | DNA repair endonuclease XPF |
UniProt Protein Name: | DNA repair endonuclease XPF |
UniProt Synonym Protein Names: | DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein |
Protein Family: | Positive control factor |
UniProt Gene Name: | ERCC4 |
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